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Protein Overview: ECM33

General Information:
Name(s) found: ECM33 / YBR078W [SGD]
Description(s) found:
Found 17 descriptions.
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  • GPI-anchored protein of unknown function, has a possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; phosphorylated in mitochondria; similar to Sps2p and Pst1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 468 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: cellular cell wall organization [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQFKNALTAT AILSASALAA NSTTSIPSSC SIGTSATATA QADLDKISGC STIVGNLTIT  60
   61 GDLGSAALAS IQEIDGSLTI FNSSSLSSFS ADSIKKITGD LNMQELIILT SASFGSLQEV 120
  121 DSINMVTLPA ISTFSTDLQN ANNIIVSDTT LESVEGFSTL KKVNVFNINN NRYLNSFQSS 180
  181 LESVSDSLQF SSNGDNTTLA FDNLVWANNI TLRDVNSISF GSLQTVNASL GFINNTLPSL 240
  241 NLTQLSKVGQ SLSIVSNDEL SKAAFSNLTT VGGGFIIANN TQLKVIDGFN KVQTVGGAIE 300
  301 VTGNFSTLDL SSLKSVRGGA NFDSSSSNFS CNALKKLQSN GAIQGDSFVC KNGATSTSVK 360
  361 LSSTSTESSK SSATSSASSS GDASNAQANV SASASSSSSS SKKSKGAAPE LVPATSFMGV 420
  421 VAAVGVAYYK IKATICVSII TLISSLMISL PFLFYYETVG SSLNFICR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ADR1 BBC1 CDC39 CDC53 CRM1 DUR1,2 ECM29 ECM33 FAA4 GAL3 GCN1 HRT1 HYP2 MDN1 MKT1 MMS1 MYO2 PFK1 PMA2 RPA190 RPN1 TPS1 UBI4 VPS13 YAR009C YGP1 YLR035C-A

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen NAF1 ECM33 2 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..91] PSI-BLAST 21.522879 No description for 1dnqA_ was found.
    2 View Details [92..468] PSI-BLAST 8.69897 Leucine rich effector protein YopM

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • receptor activity
    		•  1.46706519505919 bayes_pls_golite062009
  • binding
    		•  1.29581524164992 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.1862168530335 bayes_pls_golite062009
  • protein binding
    		•  0.853548241721519 bayes_pls_golite062009
  • signal transducer activity
    		•  0.499118819144462 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.499118819144462 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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