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Protein Overview: GAL3

General Information:
Name(s) found: GAL3 / YDR009W [SGD]
Description(s) found:
Found 31 descriptions.
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  • Transcriptional regulator involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p to relieve Gal80p inhibition of Gal4p; binds galactose and ATP but does not have galactokinase activity [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 520 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: galactose metabolic process [IMPLink to PubMed article]
    positive regulation of transcription by galactose [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: transcription activator activity [IMPLink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTNVPIFSS PVRDLPRSFE QKHLAVVDAF FQTYHVKPDF IARSPGRVNL IGEHIDYCDF  60
   61 SVLPLAIDVD MLCAVKILDE KNPSITLTNA DPKFAQRKFD LPLDGSYMAI DPSVSEWSNY 120
  121 FKCGLHVAHS YLKKIAPERF NNTPLVGAQI FCQSDIPTGG GLSSAFTCAA ALATIRANMG 180
  181 KNFDISKKDL TRITAVAEHY VGVNNGGMDQ ATSVYGEEDH ALYVEFRPKL KATPFKFPQL 240
  241 KNHEISFVIA NTLVKSNKFE TAPTNYNLRV IEVTVAANAL ATRYSVALPS HKDNSNSERG 300
  301 NLRDFMDAYY ARYENQAQPW NGDIGTGIER LLKMLQLVEE SFSRKKSGFT VHEASTALNC 360
  361 SREEFTRDYL TTFPVRFQVL KLYQRAKHVY SESLRVLKAL KMMTSATFHT DEDFFTDFGR 420
  421 LMNESQASCD KLYECSCIET NQICSIALAN GSFGSRLTGA GWGGCTIHLV PSGANGNVEQ 480
  481 VRKALIEKFY NVRYPDLTDE ELKDAIIVSK PALGTCLYEQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) GAL3 GAL4 GAL80
    View Details Ho Y, et al. (2002) ADR1 BBC1 CDC39 CDC53 CRM1 DUR1,2 ECM29 ECM33 FAA4 GAL3 GCN1 HRT1 HYP2 MDN1 MKT1 MMS1 MYO2 PFK1 PMA2 RPA190 RPN1 TPS1 UBI4 VPS13 YAR009C YGP1 YLR035C-A

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen HSH49 GAL3 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GAL3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..44]
    [71..205]    		 PSI-BLAST 62.218487 Mevalonate kinase
    2 View Details [45..70]
    [206..372]    		 PSI-BLAST 62.218487 Mevalonate kinase
    3 View Details [373..520] ORFEUS 14.1 Mevalonate kinase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle