YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rad59. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AHA1
  • cytoplasm
  • protein folding
  • response to stress
  • chaperone binding
  • chaperone activator activity
  • ATPase activator activity
  • HOM3
  • cytoplasm
  • response to drug
  • methionine metabolic process
  • threonine metabolic process
  • homoserine biosynthetic process
  • aspartate kinase activity
  • NTG1
  • nucleus
  • mitochondrion
  • DNA repair
  • base-excision repair
  • base-excision repair, AP site formation
  • oxidized pyrimidine base lesion DNA N-glycosylase activity
  • DNA-(apurinic or apyrimidinic site) lyase activity
  • oxidized purine base lesion DNA N-glycosylase activity
  • OPY1
  • cytoplasm
  • mitochondrion
  • conjugation with cellular fusion
  • molecular_function
  • PGM1
  • cytosol
  • carbohydrate metabolic process
  • glycogen biosynthetic process
  • glucose 6-phosphate metabolic process
  • galactose catabolic process
  • glucose 1-phosphate metabolic process
  • trehalose biosynthetic process
  • UDP-glucose metabolic process
  • glucose metabolic process
  • phosphoglucomutase activity
  • PGM2
  • cytosol
  • response to temperature stimulus
  • energy reserve metabolic process
  • UDP-glucose metabolic process
  • trehalose biosynthetic process
  • alcohol metabolic process
  • glucose metabolic process
  • cellular calcium ion homeostasis
  • vacuolar protein catabolic process
  • carbohydrate metabolic process
  • glycogen biosynthetic process
  • glucose 6-phosphate metabolic process
  • cellular carbohydrate metabolic process
  • galactose catabolic process
  • glucose 1-phosphate metabolic process
  • cellular cation homeostasis
  • phosphoglucomutase activity
  • PRB1
  • fungal-type vacuole lumen
  • fungal-type vacuole
  • cellular response to starvation
  • sporulation resulting in formation of a cellular spore
  • vacuolar protein catabolic process
  • serine-type endopeptidase activity
  • RAD59
  • nucleus
  • double-strand break repair via break-induced replication
  • double-strand break repair via single-strand annealing
  • telomere maintenance via recombination
  • protein binding
  • DNA strand annealing activity
  • RPB3
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • RPT3
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • SEC27
  • COPI vesicle coat
  • ER to Golgi vesicle-mediated transport
  • retrograde vesicle-mediated transport, Golgi to ER
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    glucose 6-phosphate metabolic process 2.779E-6 11 2 2 6292
    glucose 1-phosphate metabolic process 2.779E-6 11 2 2 6292
    UDP-glucose metabolic process 8.329E-6 11 3 2 6292
    galactose catabolic process 2.771E-5 11 5 2 6292
    trehalose biosynthetic process 4.1526E-5 11 6 2 6292
    glycoside biosynthetic process 4.1526E-5 11 6 2 6292
    disaccharide biosynthetic process 4.1526E-5 11 6 2 6292
    nucleotide-sugar metabolic process 5.8081E-5 11 7 2 6292
    trehalose metabolic process 9.9377E-5 11 9 2 6292
    glycoside metabolic process 1.241E-4 11 10 2 6292
    galactose metabolic process 1.5154E-4 11 11 2 6292
    disaccharide metabolic process 2.145E-4 11 13 2 6292
    vacuolar protein catabolic process 2.5001E-4 11 14 2 6292
    glycogen biosynthetic process 2.8819E-4 11 15 2 6292
    oligosaccharide biosynthetic process 3.2905E-4 11 16 2 6292
    glucan biosynthetic process 6.8913E-4 11 23 2 6292
    cellular macromolecule catabolic process 8.0284E-4 11 265 4 6292
    response to stimulus 8.5781E-4 11 766 6 6292
    catabolic process 9.2367E-4 11 496 5 6292
    oligosaccharide metabolic process 1.0247E-3 11 28 2 6292
    macromolecule catabolic process 1.1871E-3 11 294 4 6292
    glycogen metabolic process 1.3395E-3 11 32 2 6292
    cellular polysaccharide biosynthetic process 1.3395E-3 11 32 2 6292
    energy reserve metabolic process 1.3395E-3 11 32 2 6292
    polysaccharide biosynthetic process 1.6022E-3 11 35 2 6292
    glucan metabolic process 2.4131E-3 11 43 2 6292
    cellular glucan metabolic process 2.4131E-3 11 43 2 6292
    cellular protein catabolic process 2.7711E-3 11 171 3 6292
    hexose catabolic process 3.1247E-3 11 49 2 6292
    protein catabolic process 3.6833E-3 11 189 3 6292
    monosaccharide catabolic process 3.7842E-3 11 54 2 6292
    cellular polysaccharide metabolic process 3.9232E-3 11 55 2 6292
    alcohol catabolic process 4.2084E-3 11 57 2 6292
    cellular catabolic process 4.2414E-3 11 415 4 6292
    polysaccharide metabolic process 4.6539E-3 11 60 2 6292
    base-excision repair, AP site formation 5.2364E-3 11 3 1 6292
    homoserine biosynthetic process 5.2364E-3 11 3 1 6292
    cellular carbohydrate catabolic process 6.6441E-3 11 72 2 6292
    carbohydrate catabolic process 7.1927E-3 11 75 2 6292
    cellular carbohydrate biosynthetic process 7.7614E-3 11 78 2 6292
    response to stress 8.1037E-3 11 497 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    phosphoglucomutase activity 2.779E-6 11 2 2 6292
    intramolecular transferase activity, phosphotransferases 5.8081E-5 11 7 2 6292
    intramolecular transferase activity 2.8819E-4 11 15 2 6292
    aspartate kinase activity 1.7483E-3 11 1 1 6292
    oxidized pyrimidine base lesion DNA N-glycosylase activity 3.4937E-3 11 2 1 6292
    oxidized purine base lesion DNA N-glycosylase activity 3.4937E-3 11 2 1 6292
    endopeptidase activity 3.7842E-3 11 54 2 6292
    isomerase activity 4.8071E-3 11 61 2 6292
    chaperone activator activity 5.2364E-3 11 3 1 6292
    amino acid kinase activity 5.2364E-3 11 3 1 6292
    oxidized base lesion DNA N-glycosylase activity 5.2364E-3 11 3 1 6292
    DNA strand annealing activity 6.9763E-3 11 4 1 6292
    serine-type endopeptidase activity 6.9763E-3 11 4 1 6292
    phosphotransferase activity, carboxyl group as acceptor 8.7135E-3 11 5 1 6292
    DNA-(apurinic or apyrimidinic site) lyase activity 8.7135E-3 11 5 1 6292
    DNA N-glycosylase activity 8.7135E-3 11 5 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle