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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

epsilon DNA polymerase complex 7.6637E-14 4 5 4 6292
DNA polymerase complex 3.2188E-12 4 10 4 6292
nuclear replisome 4.6902E-11 4 18 4 6292
replisome 4.6902E-11 4 18 4 6292
nuclear replication fork 7.4262E-11 4 20 4 6292
nucleotide-excision repair complex 9.1735E-11 4 21 4 6292
replication fork 1.7156E-9 4 42 4 6292
protein-DNA complex 6.0545E-9 4 57 4 6292
nuclear chromosome part 8.0626E-7 4 190 4 6292
nuclear chromosome 1.6808E-6 4 228 4 6292
chromosomal part 1.9643E-6 4 237 4 6292
chromosome 3.5214E-6 4 274 4 6292
non-membrane-bounded organelle 5.368E-4 4 959 4 6292
intracellular non-membrane-bounded organelle 5.368E-4 4 959 4 6292
nuclear part 9.4015E-4 4 1103 4 6292
protein complex 1.0617E-3 4 1137 4 6292
chromatin accessibility complex 2.5411E-3 4 4 1 6292
macromolecular complex 4.5471E-3 4 1635 4 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

leading strand elongation 2.0922E-11 4 15 4 6292
lagging strand elongation 4.6902E-11 4 18 4 6292
DNA strand elongation 4.8228E-10 4 31 4 6292
DNA strand elongation involved in DNA replication 4.8228E-10 4 31 4 6292
DNA-dependent DNA replication 2.6809E-8 4 82 4 6292
DNA replication 1.3915E-7 4 123 4 6292
mismatch repair 2.8115E-7 4 27 3 6292
nucleotide-excision repair 8.0979E-7 4 38 3 6292
chromatin silencing at telomere 2.5132E-6 4 55 3 6292
negative regulation of gene expression, epigenetic 1.5407E-5 4 100 3 6292
chromatin silencing 1.5407E-5 4 100 3 6292
gene silencing 1.5407E-5 4 100 3 6292
regulation of gene expression, epigenetic 1.5407E-5 4 100 3 6292
negative regulation of transcription, DNA-dependent 5.987E-5 4 157 3 6292
negative regulation of RNA metabolic process 6.1021E-5 4 158 3 6292
negative regulation of gene expression 6.8238E-5 4 164 3 6292
negative regulation of transcription 6.8238E-5 4 164 3 6292
DNA metabolic process 7.4032E-5 4 585 4 6292
negative regulation of macromolecule biosynthetic process 8.2896E-5 4 175 3 6292
negative regulation of nitrogen compound metabolic process 9.0195E-5 4 180 3 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.0195E-5 4 180 3 6292
negative regulation of biosynthetic process 1.0438E-4 4 189 3 6292
negative regulation of cellular biosynthetic process 1.0438E-4 4 189 3 6292
DNA repair 1.0942E-4 4 192 3 6292
negative regulation of macromolecule metabolic process 1.0942E-4 4 192 3 6292
negative regulation of cellular metabolic process 1.4102E-4 4 209 3 6292
negative regulation of metabolic process 1.4305E-4 4 210 3 6292
response to DNA damage stimulus 2.027E-4 4 236 3 6292
negative regulation of cellular process 2.4072E-4 4 250 3 6292
negative regulation of biological process 2.4943E-4 4 253 3 6292
cellular response to stress 3.7451E-4 4 290 3 6292
regulation of transcription, DNA-dependent 7.0003E-4 4 358 3 6292
regulation of RNA metabolic process 7.294E-4 4 363 3 6292
cellular response to stimulus 8.288E-4 4 379 3 6292
regulation of transcription 8.6159E-4 4 384 3 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.084E-3 4 415 3 6292
regulation of nitrogen compound metabolic process 1.0917E-3 4 416 3 6292
cellular macromolecule biosynthetic process 1.2614E-3 4 1187 4 6292
macromolecule biosynthetic process 1.27E-3 4 1189 4 6292
regulation of gene expression 1.3321E-3 4 445 3 6292
regulation of macromolecule biosynthetic process 1.4316E-3 4 456 3 6292
regulation of cellular biosynthetic process 1.5848E-3 4 472 3 6292
regulation of biosynthetic process 1.5947E-3 4 473 3 6292
regulation of macromolecule metabolic process 1.7483E-3 4 488 3 6292
response to stress 1.8449E-3 4 497 3 6292
transcription, DNA-dependent 1.9112E-3 4 503 3 6292
RNA biosynthetic process 1.9676E-3 4 508 3 6292
regulation of primary metabolic process 2.0368E-3 4 514 3 6292
regulation of cellular metabolic process 2.3038E-3 4 536 3 6292
regulation of metabolic process 2.4454E-3 4 547 3 6292
transcription 2.5116E-3 4 552 3 6292
DNA synthesis involved in DNA repair 2.5411E-3 4 4 1 6292
nucleic acid metabolic process 2.5494E-3 4 1415 4 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.8261E-3 4 1566 4 6292
cellular biosynthetic process 3.8359E-3 4 1567 4 6292
biosynthetic process 4.1907E-3 4 1602 4 6292
cellular nitrogen compound metabolic process 6.2471E-3 4 1770 4 6292
response to stimulus 6.5381E-3 4 766 3 6292
nitrogen compound metabolic process 6.5492E-3 4 1791 4 6292
regulation of cellular process 7.309E-3 4 796 3 6292
regulation of biological process 8.0789E-3 4 824 3 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

double-stranded DNA binding 1.3572E-10 4 23 4 6292
structure-specific DNA binding 2.0807E-9 4 44 4 6292
DNA-directed DNA polymerase activity 8.8488E-8 4 110 4 6292
DNA polymerase activity 1.0596E-7 4 115 4 6292
nucleotidyltransferase activity 4.9077E-7 4 168 4 6292
DNA binding 2.6791E-6 4 256 4 6292
transferase activity, transferring phosphorus-containing groups 1.959E-5 4 420 4 6292
nucleic acid binding 1.2452E-4 4 666 4 6292
transferase activity 2.5575E-4 4 797 4 6292
binding 1.7823E-3 4 1294 4 6292
zinc ion binding 5.0773E-3 4 8 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle