Protein Overview: UBC9

General Information:
Name(s) found:	UBC9 / YDL064W [SGD]
Description(s) found: Found 42 descriptions. SHOW ALL	SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC) [SGD]
Organism:	Saccharomyces cerevisiae
Length:	157 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	mitotic spindle elongation [IMP] G2/M transition of mitotic cell cycle [TAS] protein sumoylation [IDA ][IMP ][IPI]
Molecular Function:	nucleotide binding [IEA] ubiquitin-protein ligase activity [RCA] ATP binding [IEA] small conjugating protein ligase activity [IEA] ligase activity [IEA] SUMO ligase activity [IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLCLQRLQ EERKKWRKDH PFGFYAKPVK KADGSMDLQK WEAGIPGKEG TNWAGGVYPI  60
   61 TVEYPNEYPS KPPKVKFPAG FYHPNVYPSG TICLSILNED QDWRPAITLK QIVLGVQDLL 120
  121 DSPNPNSPAQ EPAWRSFSRN KAEYDKKVLL QAKQYSK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	SMT3	UBC9	2	Uetz P, et al. (2000)
View Screen	RAD51	UBC9	2	Uetz P, et al. (2000)
View Screen	PRP6	UBC9	2	Uetz P, et al. (2000)
View Screen	NSE5	UBC9	2	Hazbun TR, et al. (2003)
View Screen	UBC9	UBC9	2	Uetz P, et al. (2000)
View Screen	BEM4	UBC9	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	UBC9	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..157]	PSI-BLAST	534.626727	Ubiquitin conjugating enzyme, UBC

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2