Protein Overview: P2RX2_RAT

General Information:
Name(s) found:	P2RX2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|558831\|gb\|AAA50756.1\| P2x receptor [NCBI NR] gi\|1835198\|emb\|CAA71046.1\| P2X2 receptor [Rattus norvegicus] [NCBI NR] gi\|18093098\|ref\|NP_446108.2\| purinergic receptor P2X2 [Rattus norvegicus] [NCBI NR] gi\|1352688\|sp\|P49653.1\|P2RX2_RAT RecName: Full=P2X purinoceptor 2; Short=P2X2; AltName: Full=ATP receptor; AltName: Full=Purinergic receptor [NCBI NR] gi\|1091231\|prf\|\|2020424A ATP receptor P2x [NCBI NR] pir\|\|S50859 P2x receptor - rat [NCBI NR] (P49653) P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor) [Swiss-Prot] P2X purinoceptor 2 OS=Rattus norvegicus GN=P2rx2 PE=1 SV=1 [Swiss-Prot] purinergic receptor P2X2 [HMR_022704-rand.fasta] purinergic receptor P2X2 [Rattus norvegicus]gi\|1835198\|emb\|CAA71046.1\| P2X2 receptor [Rattus norvegicus]gi\|1352688\|sp\|P49653\|P2X2_RAT P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor)gi\|1083748\|pir\|\|S50859 P2x receptor - ratgi\|558831\|gb\|A [nrdb_11152004_Chlamydomonas] (NM_053656) purinergic receptor P2X, ligand-gated ion channel, 2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] P2X purinoceptor 2 (P2X2) (ATP receptor) (Purinergic receptor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] purinergic receptor P2X2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] P2X2 receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] ATP receptor P2x [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] P2x receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor) [nr-271106-contam.fasta] purinergic receptor P2X, ligand-gated ion channel, 2 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Isoform P2RX2-1 of P2X purinoceptor 2 OS=Rattus norvegicus GN=P2rx2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	472 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] presynaptic membrane [IDA] postsynaptic density [IDA] terminal button [IDA] dendritic spine [IDA] integral to membrane [IDA] neuronal cell body [IDA] intracellular part [UNKNOWN][IEA] plasma membrane [UNKNOWN][IDA]
Biological Process:	response to organic substance [UNKNOWN] sensory perception of taste [UNKNOWN][IEA] neuromuscular synaptic transmission [UNKNOWN][IEA] response to ATP [UNKNOWN][IEA] response to carbohydrate stimulus [UNKNOWN][IEA] protein homooligomerization [UNKNOWN][IDA] synaptic transmission [UNKNOWN] protein heterooligomerization [IDA] neuromuscular junction development [UNKNOWN][IEA] detection of hypoxic conditions in blood by carotid body chemoreceptor signaling [UNKNOWN][IEA] ion transport [IEA] response to hypoxia [UNKNOWN][IEA] skeletal muscle fiber development [UNKNOWN] behavioral response to pain [UNKNOWN][IEA] urinary bladder smooth muscle contraction [UNKNOWN][IEA] peristalsis [UNKNOWN][IEA] regulation of action potential in neuron [IDA][IMP]
Molecular Function:	zinc ion binding [IDA] identical protein binding [UNKNOWN][IPI] drug binding [IDA] ligand-gated ion channel activity [IDA] phosphoinositide binding [IMP] receptor activity [IEA] extracellular ATP-gated cation channel activity [UNKNOWN][IDA][IMP] ATP binding [IDA] protein binding [IPI] copper ion binding [IDA] nickel ion binding [IDA] mercury ion binding [IDA] cadmium ion binding [IDA] cobalt ion binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRRLARGCW SAFWDYETPK VIVVRNRRLG FVHRMVQLLI LLYFVWYVFI VQKSYQDSET  60
   61 GPESSIITKV KGITMSEDKV WDVEEYVKPP EGGSVVSIIT RIEVTPSQTL GTCPESMRVH 120
  121 SSTCHSDDDC IAGQLDMQGN GIRTGHCVPY YHGDSKTCEV SAWCPVEDGT SDNHFLGKMA 180
  181 PNFTILIKNS IHYPKFKFSK GNIASQKSDY LKHCTFDQDS DPYCPIFRLG FIVEKAGENF 240
  241 TELAHKGGVI GVIINWNCDL DLSESECNPK YSFRRLDPKY DPASSGYNFR FAKYYKINGT 300
  301 TTTRTLIKAY GIRIDVIVHG QAGKFSLIPT IINLATALTS IGVGSFLCDW ILLTFMNKNK 360
  361 LYSHKKFDKV RTPKHPSSRW PVTLALVLGQ IPPPPSHYSQ DQPPSPPSGE GPTLGEGAEL 420
  421 PLAVQSPRPC SISALTEQVV DTLGQHMGQR PPVPEPSQQD STSTDPKGLA QL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: P2RX2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: