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Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts. Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient. null Catalysis of the transmembrane transfer of a cation by a channel that opens when extracellular ATP has been bound by the channel complex or one of its constituent parts. Catalysis of the transfer of metal ions from one side of a membrane to the other. Catalysis of the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts. Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: extracellular ATP-gated cation channel activity
Acc: GO:0004931
Aspect: Molecular Function
Desc: Catalysis of the transmembrane transfer of a cation by a channel that opens when extracellular ATP has been bound by the channel complex or one of its constituent parts.
Synonyms:
  • purinoreceptor
  • purinoceptor
  • P2X activity
Proteins in PDR annotated with:
   This term: 34 [Search]
   Term or descendants: 34 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004931 - extracellular ATP-gated cation channel activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle