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Protein Overview: OTX2_RAT

General Information:
Name(s) found: OTX2_RAT [Swiss-Prot]
Description(s) found:
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  • gi|3024325|sp|Q64201.1|OTX2_RAT RecName: Full=Homeobox protein OTX2; AltName: Full=Orthodenticle homolog 2 [NCBI NR]
  • Homeobox protein OTX2 (Fragment) OS=Rattus norvegicus GN=Otx2 PE=2 SV=1 [Swiss-Prot]
  • homeobox Otx2 [Rattus sp.]gi|3024325|sp|Q64201|OTX2_RAT Homeobox protein OTX2 [nrdb_11152004_Chlamydomonas]
  • Homeobox protein OTX2 (Orthodenticle homolog 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Homeobox protein OTX2 [nr-271106-contam.fasta]
  • Homeobox protein OTX2 (Fragment) OS=Rattus norvegicus GN=Otx2 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 70 amino acids

    Gene Ontology:
    Cellular Component: growth cone [UNKNOWN]
    nucleus [UNKNOWN][IEA]
    cytoplasm [UNKNOWN][IEA]
    Biological Process: multicellular organismal development [IEA]
    neuron differentiation [UNKNOWN]
    eye photoreceptor cell fate commitment [UNKNOWN][IEA]
    endoderm development [UNKNOWN][IEA]
    anterior/posterior pattern formation [UNKNOWN][IEA]
    anatomical structure development [UNKNOWN]
    axon guidance [UNKNOWN]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA]
    regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    organ morphogenesis [UNKNOWN][IEA]
    dorsal/ventral pattern formation [UNKNOWN][IEA]
    midbrain development [UNKNOWN][IEA]
    central nervous system development [UNKNOWN][IEA]
    forebrain development [UNKNOWN][IEA]
    neuron fate commitment [UNKNOWN][IEA]
    inner ear morphogenesis [UNKNOWN][IEA]
    cell fate commitment [UNKNOWN]
    cell differentiation [UNKNOWN]
    cell fate specification [UNKNOWN][IEA]
    Molecular Function: transcription factor activity [IEA]
    protein binding [UNKNOWN][IEA]
    transcription regulator activity [UNKNOWN]
    protein heterodimerization activity [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTYTQASGYS QGYAGSTSYF GGMDCGSYLT PMHHQLPGPG ATLSPMGTNA VTSHLNQSPA  60
   61 SLSTQGYGAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..70] Pfam 22.102373 No description for PF03529.4 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle