Protein Overview: NCOR1_RAT

General Information:
Name(s) found:	NCOR1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|4894626\|gb\|AAD32566.1\|AF124821_1 nuclear receptor co-repressor [Rattus norvegicus] [NCBI NR] gi\|12643492\|sp\|Q9WUB5.1\|NCOR1_RAT RecName: Full=Nuclear receptor corepressor 1; Short=N-CoR1; Short=N-CoR [NCBI NR] (Q9WUB5) Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Fragment) [Swiss-Prot] Nuclear receptor corepressor 1 (Fragment) OS=Rattus norvegicus GN=Ncor1 PE=1 SV=1 [Swiss-Prot] nuclear receptor co-repressor [Rattus norvegicus]gi\|12643492\|sp\|Q9WUB5\|NCR1_RAT Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) [nrdb_11152004_Chlamydomonas] Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] nuclear receptor co-repressor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Nuclear receptor corepressor 1 (Fragment) OS=Rattus norvegicus GN=Ncor1 [011711_HMR.fasta] Nuclear receptor corepressor 1 (Fragment) OS=Rattus norvegicus GN=Ncor1 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	533 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] spindle microtubule [UNKNOWN] nuclear part [UNKNOWN][IEA] cytoplasm [UNKNOWN][IDA] transcriptional repressor complex [UNKNOWN] histone deacetylase complex [UNKNOWN] cellular_component [ND]
Biological Process:	chromatin modification [IEA] biological_process [ND] regulation of multicellular organism growth [UNKNOWN][IEA] negative regulation of phosphoinositide 3-kinase cascade [UNKNOWN][IEA] cerebellum development [IEP] positive regulation of histone deacetylation [UNKNOWN][IEA] CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [UNKNOWN][IEA] definitive erythrocyte differentiation [UNKNOWN][IEA] regulation of transcription [IEA] negative regulation of JNK cascade [UNKNOWN] thalamus development [UNKNOWN][IEA] cholesterol homeostasis [UNKNOWN][IEA] regulation of transcription from RNA polymerase II promoter [UNKNOWN] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] spindle assembly [UNKNOWN] circadian regulation of gene expression [UNKNOWN][IEA] negative regulation of transcription, DNA-dependent [UNKNOWN] negative regulation of transcription [IMP] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN]
Molecular Function:	histone deacetylase regulator activity [UNKNOWN][IEA] protein domain specific binding [IEA] histone deacetylase binding [UNKNOWN] sequence-specific DNA binding [UNKNOWN] retinoic acid receptor binding [UNKNOWN] retinoid X receptor binding [UNKNOWN][IEA] thyroid hormone receptor binding [UNKNOWN][IEA] DNA binding [UNKNOWN][IEA] transcription factor activity [UNKNOWN][IEA] protein binding [UNKNOWN][NAS] transcription corepressor activity [UNKNOWN][IEA] promoter binding [IEA] transcription repressor activity [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDKGPPPKSR YEEELRTRGK TTITAANFID VIITRQIASD KDARERGSQS SDSSSSLSSH  60
   61 RYEAPSDAIE VISPASSPAP PQEKPQTYQP EMVKANQAEN ESPQQYEGPL THYRSQQGSP 120
  121 SPQQQPPLPP SSQAEGMGQV PRTHRLITLA DHICQIITQD FARNQVPSQP STSTFQTSPS 180
  181 ALSSTPVRTK PSSRYSPESQ SQTVLHPRPG PRVSPENLVD KSRGSRPGKS PERSHIPSEP 240
  241 YEPISPPQGP AVHEKQDSML LLSQRGMDPA EQRSDSRSPG SISYLPYFFT KLESTSPMVK 300
  301 SKKQEIFRKL NSSGGGDSDM AAAQPGTEIF NLPAVTTSGA VSSRSHSFAD PASNLGLEDI 360
  361 IRKALMGSFD DKVEDHGVVM PHPVGVVPGS ASTSVVTSSE TRRDEGDPSP HSGVCKPKLI 420
  421 NKSNSRKSKS PIPGQNYLGT ERPSSVSSVH SEGDYHRQTP GWAWEDRPSS TGSTQFPYNP 480
  481 LTIRMLSSTP PTPIACAPSA ITQAAPHQQS RIWEREPAPL LSAQYETLSD SDD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: NCOR1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: