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Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. Any process that stops, prevents or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. The process by which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types. The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell. The process by which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell. The process whereby a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell. The process whereby a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell. The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell during an immune response. Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
Acc: GO:0002361
Aspect: Biological Process
Desc: The process whereby a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
Synonyms:
  • CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation
  • CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation
  • CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002361 - CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (interactive image map)
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