General Information: |
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Name(s) found: |
DRD2_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 444 amino acids |
Gene Ontology: |
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Cellular Component: |
postsynaptic density
[IDA]
lateral plasma membrane [IMP] perikaryon [IDA] plasma membrane [IDA] axon terminus [IDA] integral to plasma membrane [UNKNOWN] endocytic vesicle [IDA] dendrite [UNKNOWN][IDA] soluble fraction [IDA] acrosomal vesicle [IDA] membrane [UNKNOWN][IDA] dendritic spine [IDA] integral to membrane [IEA] flagellum [IDA] cytoplasmic vesicle [IDA] synaptic vesicle membrane [IDA] axon [UNKNOWN][IDA] |
Biological Process: |
dopamine metabolic process
[UNKNOWN][IEA]
positive regulation of growth hormone secretion [UNKNOWN][IEA] negative regulation of calcium ion transport via voltage-gated calcium channel activity [UNKNOWN][IDA] dopamine receptor signaling pathway [UNKNOWN][IDA][IMP][TAS] protein localization [UNKNOWN][IEA] regulation of potassium ion transport [UNKNOWN][IDA] visual learning [UNKNOWN][IEA] response to axon injury [IEP] branching morphogenesis of a nerve [UNKNOWN][IEA] positive regulation of mitosis [TAS] associative learning [UNKNOWN][IEA] regulation of phosphoprotein phosphatase activity [IMP] response to toxin [IEP] circadian regulation of gene expression [UNKNOWN][IEA] response to hypoxia [IMP] forebrain development [IMP] regulation of long-term neuronal synaptic plasticity [UNKNOWN][IEA] axonogenesis [UNKNOWN][IEA] pigmentation [UNKNOWN][IEA] elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger [UNKNOWN] sensory perception of smell [UNKNOWN][IEA] Wnt receptor signaling pathway [IDA] phosphoinositide metabolic process [IDA] negative regulation of synaptic transmission, glutamatergic [UNKNOWN][IEA] release of sequestered calcium ion into cytosol [IMP] natriuresis [UNKNOWN][IEA] diuresis [UNKNOWN][IEA] G-protein coupled receptor protein signaling pathway [UNKNOWN][IEA] positive regulation of receptor internalization [IMP] adenohypophysis development [UNKNOWN][IEA] response to cocaine [UNKNOWN] positive regulation of neuroblast proliferation [UNKNOWN][IEA] negative regulation of blood pressure [UNKNOWN][IEA] G-protein signaling, coupled to cAMP nucleotide second messenger [IDA] response to morphine [UNKNOWN][IEA] activation of phospholipase C activity by dopamine receptor signaling pathway [UNKNOWN][IEA] long-term memory [IMP] synapse assembly [IEP] arachidonic acid secretion [UNKNOWN] regulation of cAMP metabolic process [UNKNOWN] response to histamine [UNKNOWN] auditory behavior [IMP] regulation of synaptic transmission [UNKNOWN][IDA] negative regulation of dopamine receptor signaling pathway [UNKNOWN][IEA] negative regulation of cell migration [UNKNOWN][IEA] adult behavior [UNKNOWN] negative regulation of protein kinase B signaling cascade [UNKNOWN][IEA] nerve-nerve synaptic transmission [UNKNOWN] negative regulation of adenylate cyclase activity [UNKNOWN][IDA] regulation of MAPKKK cascade [IDA] acid secretion [IDA] inhibition of adenylate cyclase activity by dopamine receptor signaling pathway [UNKNOWN][IDA] negative regulation of cell proliferation [UNKNOWN][IEA] feeding behavior [UNKNOWN][IEA] cerebral cortex GABAergic interneuron migration [UNKNOWN][IEA] negative regulation of insulin secretion [IMP] positive regulation of transcription from RNA polymerase II promoter [IDA] response to light stimulus [UNKNOWN][IEA] positive regulation of multicellular organism growth [UNKNOWN][IEA] positive regulation of G-protein coupled receptor protein signaling pathway [IMP] adult walking behavior [UNKNOWN][IEA] cellular potassium ion homeostasis [IC] response to ethanol [IEP] grooming behavior [UNKNOWN][IEA] synaptic transmission, dopaminergic [IDA][IMP] locomotory behavior [UNKNOWN][IMP] positive regulation of dopamine uptake [UNKNOWN][IEA] startle response [UNKNOWN] behavioral response to cocaine [UNKNOWN][IEA] regulation of dopamine uptake [UNKNOWN] response to iron ion [IEP] activation of protein kinase activity [IDA] regulation of synaptic transmission, GABAergic [UNKNOWN][IEA] regulation of dopamine secretion [UNKNOWN][IEA] prepulse inhibition [UNKNOWN][IEA] signal transduction [IEA] negative regulation of protein secretion [UNKNOWN] reduction of cytosolic calcium ion concentration [IMP] G-protein coupled receptor internalization [IDA] intracellular protein kinase cascade [UNKNOWN] negative regulation of circadian sleep/wake cycle, sleep [IDA] response to nicotine [IEP] behavioral response to ethanol [UNKNOWN][IEA] regulation of heart rate [UNKNOWN][IEA] regulation of sodium ion transport [UNKNOWN][IEA] response to amphetamine [UNKNOWN][IEP] neurological system process involved in regulation of systemic arterial blood pressure [UNKNOWN][IEA] response to drug [UNKNOWN][IDA] temperature homeostasis [UNKNOWN][IEA] positive regulation of ERK1 and ERK2 cascade [IMP] peristalsis [UNKNOWN][IEA] |
Molecular Function: |
G-protein coupled receptor activity
[UNKNOWN][IEA]
dopamine receptor activity [UNKNOWN][IEA][IMP] ionotropic glutamate receptor binding [IPI] protein binding [UNKNOWN][IPI][TAS] drug binding [UNKNOWN][IDA] dopamine binding [UNKNOWN][IMP] dopamine receptor activity, coupled via Gi/Go [UNKNOWN][IDA] dopamine D2 receptor activity [UNKNOWN][IDA] receptor activity [IEA] receptor binding [IPI] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MDPLNLSWYD DDLERQNWSR PFNGSEGKAD RPHYNYYAML LTLLIFIIVF GNVLVCMAVS 60 61 REKALQTTTN YLIVSLAVAD LLVATLVMPW VVYLEVVGEW KFSRIHCDIF VTLDVMMCTA 120 121 SILNLCAISI DRYTAVAMPM LYNTRYSSKR RVTVMIAIVW VLSFTISCPL LFGLNNTDQN 180 181 ECIIANPAFV VYSSIVSFYV PFIVTLLVYI KIYIVLRKRR KRVNTKRSSR AFRANLKTPL 240 241 KGNCTHPEDM KLCTVIMKSN GSFPVNRRRM DAARRAQELE MEMLSSTSPP ERTRYSPIPP 300 301 SHHQLTLPDP SHHGLHSNPD SPAKPEKNGH AKIVNPRIAK FFEIQTMPNG KTRTSLKTMS 360 361 RRKLSQQKEK KATQMLAIVL GVFIICWLPF FITHILNIHC DCNIPPVLYS AFTWLGYVNS 420 421 AVNPIIYTTF NIEFRKAFMK ILHC |
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