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Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. Any process by which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain. The part of the circadian sleep/wake cycle where the organism is asleep. Any process that stops, prevents or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any biological process, occurring at the level of a multicellular organism, pertinent to its function. Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep. Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep. Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. Any process that stops, prevents or reduces the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli. Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli. Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle. Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours. Any biological process in an organism that recurs with a regularity of approximately 24 hours. The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. Any process that stops, prevents or reduces the frequency, rate or extent of a circadian rhythm behavior.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of circadian sleep/wake cycle, sleep
Acc: GO:0042321
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
Synonyms:
  • inhibition of circadian sleep/wake cycle, sleep
  • negative regulation of sleep
  • down-regulation of circadian sleep/wake cycle, sleep
  • downregulation of circadian sleep/wake cycle, sleep
  • down regulation of circadian sleep/wake cycle, sleep
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042321 - negative regulation of circadian sleep/wake cycle, sleep (interactive image map)
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