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Protein Overview: CE37093

General Information:
Name(s) found: CE37093 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00016030 status:Confirmed UniProt:Q6A591 protein_id:CCD65364.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 765 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: signal transduction [IEALink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    non-membrane spanning protein tyrosine kinase activity [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNYKSRPLT SCSDELKKKI SEGYSVVRSR LSDDVRSRSN LGWVDVQIAA FEKSLEDFKQ  60
   61 HMCPENAELK STQLLSLFHI ICAGHSDSQP EKLQFLIDNL PKESSITLIS SQSANGFTPL 120
  121 HIAIYRGDVA ILKALIATKL VDLDQSGRHL LPALHLAAMI GDSEMLTILL NSGANIHVTD 180
  181 FVHFTALHCA TYFGQENAVR TLISASANLN LGGAVNDRPI HLAAAKGLTS ITKLLLEAKA 240
  241 DPLLADDEGN QALHYAAKSG SLVILNMLIK QVRGTNDRIC ARNLYGDTAL HLSCYSGRLD 300
  301 IVKSILDSSP TNIVNMENVF SETPLHAACT GGKSIELVSF LMKYPGVDPN YQGQDGHTAL 360
  361 HSACYHGHLR IVQYLLENGA DQSLASRAFE GGALRQQAGP GTNRPSKVAS AIMALNRSDT 420
  421 PSSNASYNST VSLDDQQTPV IWAYERGHDA IVALLKHYAA RTVEGDVCSE YSSGESSYTP 480
  481 LPSPMGRLTS LTRDKADLLQ LRSALPAPFH LCLAEIEFQE SIGSGSFGKV YKGTYRGKLV 540
  541 AVKRYRAMAF GCKSETDMLC REVSILSRLA HPNVVAFVGT SLDDPSQFAI ITEFVENGSL 600
  601 FRLLHEEKRV MDPAFRLRIS LDVARGMRYL HESAAKPVIH RDLNSHNILI HADGRSVVAD 660
  661 FGESRFVCQR EDENLTKQPG NLRWMAPEVF SQSGKYDRKV DVFSFALVIW EIHTAELPFS 720
  721 HRYKCSFYSI PVDISMGAAK RGTSPRVKVP ANSLGVTWDR CYGNR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..481] PSI-BLAST 88.522879 Ankyrin-R
    2 View Details [482..765] PSI-BLAST 27.09691 Hemapoetic cell kinase Hck; Hemopoetic cell kinase Hck; Haemopoetic cell kinase Hck

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  3.30812396303844 bayes_pls_golite062009
  • actin binding
    		•  3.15358758538214 bayes_pls_golite062009
  • structural constituent of muscle
    		•  2.72158799470339 bayes_pls_golite062009
  • protein binding
    		•  2.69918165732603 bayes_pls_golite062009
  • binding
    		•  2.60916417202222 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  2.4948065111495 bayes_pls_golite062009
  • actin filament binding
    		•  1.8758804992293 bayes_pls_golite062009
  • myosin binding
    		•  1.55894148251645 bayes_pls_golite062009
  • protein kinase activity
    		•  1.44085162459605 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.4354270769219 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.24901082343235 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.2375987667709 bayes_pls_golite062009
  • signal transducer activity
    		•  1.2375987667709 bayes_pls_golite062009
  • receptor activity
    		•  1.22857731988464 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.22209007484238 bayes_pls_golite062009
  • kinase activity
    		•  1.20122575201235 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.10325771560525 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.08563335973815 bayes_pls_golite062009
  • DNA binding
    		•  1.02969244915531 bayes_pls_golite062009
  • myosin phosphatase activity
    		•  0.991228379874891 bayes_pls_golite062009
  • structural molecule activity
    		•  0.808967137205604 bayes_pls_golite062009
  • transporter activity
    		•  0.782432203646924 bayes_pls_golite062009
  • protein kinase binding
    		•  0.78130842943004 bayes_pls_golite062009
  • kinase binding
    		•  0.75961315755729 bayes_pls_golite062009
  • ion channel activity
    		•  0.73200897518931 bayes_pls_golite062009
  • transcription factor binding
    		•  0.71111931011795 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.653190853243002 bayes_pls_golite062009
  • gated channel activity
    		•  0.61949975977518 bayes_pls_golite062009
  • transcription factor activity
    		•  0.614673057254056 bayes_pls_golite062009
  • enzyme binding
    		•  0.60140077251711 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.5337972579854 bayes_pls_golite062009
  • cation channel activity
    		•  0.529463527277151 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.515634991066501 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.375391185084903 bayes_pls_golite062009
  • transferase activity
    		•  0.291085370218412 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.238966076323951 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.108244697820437 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.0675641359654993 bayes_pls_golite062009
  • channel activity
    		•  0.0675641359654993 bayes_pls_golite062009
  • protein serine/threonine kinase inhibitor activity
    		•  0.0500658306142403 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  0.0462605323512499 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.0018080615624233 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle