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Protein Overview: CP511_ARATH

General Information:
Name(s) found: CP511_ARATH [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • Sterol 14-demethylase OS=Arabidopsis thaliana GN=CYP51G1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 488 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDA]
    plasma membrane [IDA]
    Biological Process: embryonic development ending in seed dormancy [NAS]
    sterol biosynthetic process [IMP][TAS]
    Molecular Function: oxygen binding [ISS]
    sterol 14-demethylase activity [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELDSENKLL KTGLVIVATL VIAKLIFSFF TSDSKKKRLP PTLKAWPPLV GSLIKFLKGP  60
   61 IIMLREEYPK LGSVFTVNLV HKKITFLIGP EVSAHFFKAS ESDLSQQEVY QFNVPTFGPG 120
  121 VVFDVDYSVR QEQFRFFTEA LRVNKLKGYV DMMVTEAEDY FSKWGESGEV DIKVELERLI 180
  181 ILTASRCLLG REVRDQLFDD VSALFHDLDN GMLPISVLFP YLPIPAHRRR DRAREKLSEI 240
  241 FAKIIGSRKR SGKTENDMLQ CFIESKYKDG RQTTESEVTG LLIAALFAGQ HTSSITSTWT 300
  301 GAYLMRYKEY FSAALDEQKN LIAKHGDKID HDILSEMDVL YRCIKEALRL HPPLIMLMRA 360
  361 SHSDFSVTAR DGKTYDIPKG HIVATSPAFA NRLPHIFKDP DTYDPERFSP GREEDKAAGA 420
  421 FSYIAFGGGR HGCLGEPFAY LQIKAIWSHL LRNFELELVS PFPEIDWNAM VVGVKGNVMV 480
  481 RYKRRQLS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..488] PSI-BLAST 61.221849 Cytochrome p450 14 alpha-sterol demethylase (cyp51)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  5.03099580095037 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  3.76307535769621 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  3.51923259313626 bayes_pls_golite062009
  • demethylase activity
    		•  3.40807632433846 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.24344797738248 bayes_pls_golite062009
  • retinoic acid binding
    		•  3.04897926497756 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  2.94610675710811 bayes_pls_golite062009
  • retinoid binding
    		•  2.60220937953757 bayes_pls_golite062009
  • isoprenoid binding
    		•  2.47826119804163 bayes_pls_golite062009
  • corticosterone 18-monooxygenase activity
    		•  2.39818079128436 bayes_pls_golite062009
  • steroid 11-beta-monooxygenase activity
    		•  2.39818079128436 bayes_pls_golite062009
  • arachidonic acid monooxygenase activity
    		•  2.39688955430367 bayes_pls_golite062009
  • steroid 7-alpha-hydroxylase activity
    		•  2.29989218606587 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.09151585300316 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  2.036553099796 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  1.97593187367475 bayes_pls_golite062009
  • oxygen binding
    		•  1.66120675703571 bayes_pls_golite062009
  • electron carrier activity
    		•  1.48516712188486 bayes_pls_golite062009
  • binding
    		•  1.2866152532988 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  1.02400450548438 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  0.79568492499797 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
    		•  0.169431271735966 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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