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Protein Overview: RFA1B_ARATH

General Information:
Name(s) found: RFA1B_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
SHOW ALL
  • Replication protein A 70 kDa DNA-binding subunit B OS=Arabidopsis thaliana GN=RPA1B PE=3 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 604 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: DNA repair [TAS]
    DNA replication [ISS]
    response to UV-B [IMP]
    Molecular Function: nucleic acid binding [IEA]
    DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENSVTQDGI ATVLANQSLD SSSVRPEIVV QVVDLKPAGN RYTFSANDGK MKIKAMLPAT  60
   61 LTSDIISGKI QNLGLIRLLE YTVNDIPGKS EEKYMLITKC EAVASALDSE IKAEIKASTG 120
  121 IMLKPKHEFV AKSASQIINE QRGNAAPAAR MAMTRRVHPL VSLNPYQGSW TIKVRVTNKG 180
  181 VMRTYKNARG EGCVFNVELT DEEGTQIQAT MFNAAARKFY DRFEMGKVYY ISRGSLKLAN 240
  241 KQFKTVQNDY EMTLNENSEV EEASNEEMFT PETKFNFVPI DELGTYVNQK DLIDVIGVVQ 300
  301 SVSPTMSIRR KNDNEMIPKR DITLADETKK TVVVSLWNDL ATGIGQELLD MADNHPVIAI 360
  361 KSLKVGAFQG VSLSTISRSN VVINPNSPEA TKLKSWYDAE GKETSMSAIG SGMSSSANNG 420
  421 SRSMYSDRVF LSHITSNPSL GEEKPVFFST RAYISFIKPD QTMWYRACKT CNKKVTEAMD 480
  481 SGYWCESCQK KDQECSLRYI MAVKVSDSTG ETWLSAFNDE AEKIIGCTAD DLNDLKSEEG 540
  541 EVNEFQTKLK EATWSSHLFR ISVSQQEYNS EKRQRITVRG VSPIDFAAET RLLLQDISKN 600
  601 KTSQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..150] PSI-BLAST 26.154902 N-terminal domain of the RPA70 subunit of human replication protein A.
    2 View Details [151..398] PSI-BLAST 58.0 Replication protein A 70 KDa subunit (RPA70)
    3 View Details [399..604] PSI-BLAST 43.69897 Replication protein A 70 KDa subunit (RPA70)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • telomeric DNA binding
    		•  7.07761964836826 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
    		•  6.04637014849887 bayes_pls_golite062009
  • telomerase inhibitor activity
    		•  4.06762092339715 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.02967008021862 bayes_pls_golite062009
  • DNA binding
    		•  3.62735703519187 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  3.59212997362902 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  3.53214384646348 bayes_pls_golite062009
  • binding
    		•  2.83465364476231 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.20239961025491 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.13063800565247 bayes_pls_golite062009
  • structural molecule activity
    		•  1.9177190829469 bayes_pls_golite062009
  • protein binding
    		•  1.20309946451799 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.19236946227657 bayes_pls_golite062009
  • DNA helicase activity
    		•  1.12203697857261 bayes_pls_golite062009
  • transcription factor activity
    		•  1.05816813143865 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.86170694706755 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.638831894247026 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.378383789953688 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.325774164899685 bayes_pls_golite062009
  • four-way junction helicase activity
    		•  0.31769813397725 bayes_pls_golite062009
  • translation regulator activity
    		•  0.31332179848255 bayes_pls_golite062009
  • RNA binding
    		•  0.31028563542112 bayes_pls_golite062009
  • exonuclease activity
    		•  0.28313884527829 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.263197317040851 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.2080607201312 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.125256208482441 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.109774918833391 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.0954216620147701 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.0179535526984695 bayes_pls_golite062009
  • helicase activity
    		•  0.0121541775159524 bayes_pls_golite062009
    2
    Term Confidence Notes
  • telomeric DNA binding
    		•  7.07761964836826 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
    		•  6.04637014849887 bayes_pls_golite062009
  • telomerase inhibitor activity
    		•  4.06762092339715 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.02967008021862 bayes_pls_golite062009
  • DNA binding
    		•  3.62735703519187 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  3.59212997362902 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  3.53214384646348 bayes_pls_golite062009
  • binding
    		•  2.83465364476231 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.20239961025491 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.13063800565247 bayes_pls_golite062009
  • structural molecule activity
    		•  1.9177190829469 bayes_pls_golite062009
  • protein binding
    		•  1.20309946451799 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.19236946227657 bayes_pls_golite062009
  • DNA helicase activity
    		•  1.12203697857261 bayes_pls_golite062009
  • transcription factor activity
    		•  1.05816813143865 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.86170694706755 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.638831894247026 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.378383789953688 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.325774164899685 bayes_pls_golite062009
  • four-way junction helicase activity
    		•  0.31769813397725 bayes_pls_golite062009
  • translation regulator activity
    		•  0.31332179848255 bayes_pls_golite062009
  • RNA binding
    		•  0.31028563542112 bayes_pls_golite062009
  • exonuclease activity
    		•  0.28313884527829 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.263197317040851 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.2080607201312 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.125256208482441 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.109774918833391 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.0954216620147701 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.0179535526984695 bayes_pls_golite062009
  • helicase activity
    		•  0.0121541775159524 bayes_pls_golite062009
    3
    Term Confidence Notes
  • telomeric DNA binding
    		•  7.07761964836826 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
    		•  6.04637014849887 bayes_pls_golite062009
  • telomerase inhibitor activity
    		•  4.06762092339715 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.02967008021862 bayes_pls_golite062009
  • DNA binding
    		•  3.62735703519187 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  3.59212997362902 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  3.53214384646348 bayes_pls_golite062009
  • binding
    		•  2.83465364476231 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.20239961025491 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.13063800565247 bayes_pls_golite062009
  • structural molecule activity
    		•  1.9177190829469 bayes_pls_golite062009
  • protein binding
    		•  1.20309946451799 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.19236946227657 bayes_pls_golite062009
  • DNA helicase activity
    		•  1.12203697857261 bayes_pls_golite062009
  • transcription factor activity
    		•  1.05816813143865 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.86170694706755 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.638831894247026 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.378383789953688 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.325774164899685 bayes_pls_golite062009
  • four-way junction helicase activity
    		•  0.31769813397725 bayes_pls_golite062009
  • translation regulator activity
    		•  0.31332179848255 bayes_pls_golite062009
  • RNA binding
    		•  0.31028563542112 bayes_pls_golite062009
  • exonuclease activity
    		•  0.28313884527829 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.263197317040851 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.2080607201312 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.125256208482441 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.109774918833391 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.0954216620147701 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.0179535526984695 bayes_pls_golite062009
  • helicase activity
    		•  0.0121541775159524 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle