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Protein Overview: AMPL1_ARATH

General Information:
Name(s) found: AMPL1_ARATH [Swiss-Prot]
Description(s) found:
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  • pir||S22399 leucyl aminopeptidase (EC 3.4.11.1) - Arabidopsis thaliana [NCBI NR]
  • gi|4115380|gb|AAD03381.1| putative leucine aminopeptidase [Arabidopsis thaliana] [NCBI NR]
  • gi|30102470|gb|AAP21153.1| At2g24200/F27D4.11 [Arabidopsis thaliana] [NCBI NR]
  • gi|231536|sp|P30184.1|AMPL1_ARATH RecName: Full=Leucine aminopeptidase 1; AltName: Full=Leucyl aminopeptidase 1; Short=LAP 1; AltName: Full=Proline aminopeptidase 1; AltName: Full=Prolyl aminopeptidase 1 [NCBI NR]
  • gi|186502696|ref|NP_001118375.1| cytosol aminopeptidase [Arabidopsis thaliana] [NCBI NR]
  • gi|17063168|gb|AAL32980.1| At2g24200/F27D4.11 [Arabidopsis thaliana] [NCBI NR]
  • gi|16394|emb|CAA45040.1| leucine aminopeptidase [Arabidopsis thaliana] [NCBI NR]
  • gi|15224101|ref|NP_179997.1| cytosol aminopeptidase [Arabidopsis thaliana] [NCBI NR]
  • (P30184) Cytosol aminopeptidase (EC 3.4.11.1) (Leucine aminopeptidase) (LAP) (Leucyl aminopeptidase) (Proline aminopeptidase) (EC 3.4.11.5) (Prolyl aminopeptidase) [Swiss-Prot]
  • Leucine aminopeptidase 1 OS=Arabidopsis thaliana GN=PM25 PE=1 SV=1 [Swiss-Prot]
  • At2g24200/F27D4.11 [Arabidopsis thaliana]gi|16394|emb|CAA45040.1| leucine aminopeptidase [Arabidopsis thaliana]gi|4115380|gb|AAD03381.1| putative leucine aminopeptidase [Arabidopsis thaliana]gi|17063168|gb|AAL32980.1| At2g24200/F27D4.11 [Arabidopsis th [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Cytosol aminopeptidase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: | cytosol aminopeptidase | chr2:10294097-10296530 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • aminopeptidase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • leucine aminopeptidase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative leucine aminopeptidase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At2g24200/F27D4.11 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Leucine aminopeptidase 1 (LAP 1) (Leucyl aminopeptidase 1) (Proline aminopeptidase 1) (Prolyl aminopeptidase 1) [nr-271106-contam.fasta]
  • | Symbols: | Cytosol aminopeptidase family protein | chr2:10287017-10289450 REVERSE LENGTH=520 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Leucine aminopeptidase 1 OS=Arabidopsis thaliana GN=PM25 PE=2 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 520 amino acids

    Gene Ontology:
    Cellular Component: vacuole [IDA]
    Biological Process: proteolysis [ISS]
    response to cadmium ion [IEP]
    Molecular Function: metalloexopeptidase activity [IEA]
    manganese ion binding [IEA]
    aminopeptidase activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHTLGLTQP NSTEPHKISF TAKEIDVIEW KGDILVVGVT EKDLAKDGNS KFENPILSKV  60
   61 DAHLSGLLAQ VSSEEDFTGK PGQSTVLRLP GLGSKRIALI GLGQSVSSPV AFHSLGEAVA 120
  121 TVSKASQSTS AAIVLASSVS DESKLSSVSA LASGIVLGLF EDGRYKSESK KPSLKAVDII 180
  181 GFGTGAEVEK KLKYAEDVSY GVIFGRELIN SPANVLTPAV LAEEAAKVAS TYSDVFTANI 240
  241 LNEEQCKELK MGSYLAVAAA SANPPHFIHL VYKPPNGSVK TKLALVGKGL TFDSGGYNIK 300
  301 TGPGCSIELM KFDMGGSAAV LGAAKAIGEI KPPGVEVHFI VAACENMISG TGMRPGDVIT 360
  361 ASNGKTIEVN NTDAEGRLTL ADALVYACNQ GVDKIVDLAT LTGACVIALG TSMAGIYTPS 420
  421 DELAKEVIAA SERSGEKLWR MPLEESYWEM MKSGVADMVN TGGRAGGSIT AALFLKQFVS 480
  481 EKVQWMHIDM AGPVWNEKKK SGTGFGVATL VEWVQKNSSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..520] PSI-BLAST 170.0 Leucine aminopeptidase, C-terminal domain; Leucine aminopeptidase (Aminopeptidase A), N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  3.33046421415418 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.92029075689694 bayes_pls_golite062009
  • hydrolase activity
    		•  2.67636468634585 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.92607656615233 bayes_pls_golite062009
  • catalytic activity
    		•  1.76936806579991 bayes_pls_golite062009
  • metallopeptidase activity
    		•  1.36622846208556 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  1.26773013808101 bayes_pls_golite062009
  • metalloexopeptidase activity
    		•  0.675221914435689 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.655590943576337 bayes_pls_golite062009
  • binding
    		•  0.512335905288743 bayes_pls_golite062009
  • metallocarboxypeptidase activity
    		•  0.406156022753981 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.0365339945959349 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle