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Protein Overview: 14338_ARATH

General Information:
Name(s) found: 14338_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|5802794|gb|AAD51783.1|AF145300_1 14-3-3 protein GF14 kappa [Arabidopsis thaliana] [NCBI NR]
  • gi|30698122|ref|NP_851274.1| GRF8 (GENERAL REGULATORY FACTOR 8); protein binding / protein phosphorylated amino acid binding [Arabidopsis thaliana] [NCBI NR]
  • gi|21537301|gb|AAM61642.1| 14-3-3 protein GF14kappa (grf8) [Arabidopsis thaliana] [NCBI NR]
  • gi|19310701|gb|AAL85081.1| putative 14-3-3 protein GF14kappa [Arabidopsis thaliana] [NCBI NR]
  • gi|15293125|gb|AAK93673.1| putative 14-3-3 protein GF14kappa grf8 [Arabidopsis thaliana] [NCBI NR]
  • gi|12643286|sp|P48348.2|14338_ARATH RecName: Full=14-3-3-like protein GF14 kappa; AltName: Full=General regulatory factor 8 [NCBI NR]
  • (P48348) 14-3-3-like protein GF14 kappa (General regulatory factor 8) [Swiss-Prot]
  • 14-3-3-like protein GF14 kappa OS=Arabidopsis thaliana GN=GRF8 PE=1 SV=2 [Swiss-Prot]
  • 14-3-3 protein GF14kappa (grf8) [Arabidopsis thaliana]gi|19310701|gb|AAL85081.1| putative 14-3-3 protein GF14kappa [Arabidopsis thaliana]gi|15293125|gb|AAK93673.1| putative 14-3-3 protein GF14kappa grf8 [Arabidopsis thaliana]gi|5802794|gb|AAD51783.1| 1 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Splice Isoform 1 of 14-3-3-like protein GF14 kappa [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: GF14 KAPPA, GRF8 | GRF8 (GENERAL REGULATORY FACTOR 8); protein phosphorylated amino acid binding | chr5:26165772-26167481 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • putative 14-3-3 protein GF14kappa [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • 14-3-3 protein GF14kappa (grf8) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • GRF8; protein phosphorylated amino acid binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative 14-3-3 protein GF14kappa grf8 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • 14-3-3 protein GF14 kappa [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • 14-3-3-like protein GF14 kappa (General regulatory factor 8) [nr-271106-contam.fasta]
  • | Symbols: GRF8, 14-3-3KAPPA, GF14 KAPPA | general regulatory factor 8 | chr5:26148546-26150255 REVERSE LENGTH=248 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • 14-3-3-like protein GF14 kappa OS=Arabidopsis thaliana GN=GRF8 PE=2 SV=2 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 248 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    chloroplast [IDA]
    cytoplasm [IDA]
    cell wall [IDA]
    plant-type cell wall [IDA]
    plasma membrane [IDA]
    Biological Process: brassinosteroid mediated signaling pathway [IPI]
    Molecular Function: protein binding [NAS]
    protein phosphorylated amino acid binding [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATTLSRDQY VYMAKLAEQA ERYEEMVQFM EQLVSGATPA GELTVEERNL LSVAYKNVIG  60
   61 SLRAAWRIVS SIEQKEESRK NEEHVSLVKD YRSKVETELS SICSGILRLL DSHLIPSATA 120
  121 SESKVFYLKM KGDYHRYLAE FKSGDERKTA AEDTMIAYKA AQDVAVADLA PTHPIRLGLA 180
  181 LNFSVFYYEI LNSSEKACSM AKQAFEEAIA ELDTLGEESY KDSTLIMQLL RDNLTLWTSD 240
  241 MQEQMDEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..248] PSI-BLAST 111.0 14-3-3-like protein C

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • tryptophan hydroxylase activator activity
    		•  9.05098057244127 bayes_pls_golite062009
  • protein kinase C inhibitor activity
    		•  5.16790132127192 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.42699469191586 bayes_pls_golite062009
  • actin binding
    		•  3.2102277095412 bayes_pls_golite062009
  • phosphoprotein phosphatase inhibitor activity
    		•  3.07610360813748 bayes_pls_golite062009
  • enzyme inhibitor activity
    		•  3.01719375125219 bayes_pls_golite062009
  • binding
    		•  2.865609797812 bayes_pls_golite062009
  • protein binding
    		•  2.70837661160137 bayes_pls_golite062009
  • phosphatase inhibitor activity
    		•  2.64873378059247 bayes_pls_golite062009
  • steroid hormone receptor binding
    		•  2.52034336284118 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.47421036599568 bayes_pls_golite062009
  • protein serine/threonine kinase inhibitor activity
    		•  2.26190206574987 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.24952329412422 bayes_pls_golite062009
  • protein kinase inhibitor activity
    		•  2.1605779239681 bayes_pls_golite062009
  • kinase inhibitor activity
    		•  2.13634503016902 bayes_pls_golite062009
  • DNA binding
    		•  2.12868741280915 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.06101279275497 bayes_pls_golite062009
  • receptor binding
    		•  1.90211144110648 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  1.89095665930248 bayes_pls_golite062009
  • kinase regulator activity
    		•  1.83999438696779 bayes_pls_golite062009
  • nuclear hormone receptor binding
    		•  1.82791045779247 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.77196747521243 bayes_pls_golite062009
  • hormone receptor binding
    		•  1.75728917995967 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.58823136201189 bayes_pls_golite062009
  • transcription activator activity
    		•  1.55295513057402 bayes_pls_golite062009
  • enzyme binding
    		•  0.97087555033584 bayes_pls_golite062009
  • transcription factor binding
    		•  0.644366120007212 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.549856334651464 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.493085020732158 bayes_pls_golite062009
  • catalytic activity
    		•  0.260308151913118 bayes_pls_golite062009
  • glucocorticoid receptor binding
    		•  0.201948675373558 bayes_pls_golite062009
  • insulin-like growth factor receptor binding
    		•  0.115610219048892 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle