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Protein Overview: nas-7

General Information:
Name(s) found: nas-7 / CE34663 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00003526 locus:nas-7 Zinc metalloproteinase nas-7 status:Partially_confirmed UniProt:P55113 protein_id:CCD63532.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 382 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEALink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    astacin activity [IEALink to PubMed article]
    metallopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLPWIITIV TVIPATLGHR NRVQDDEMLV ISDSTDSLNL EDFEFADKLT REELFGKHIP  60
   61 VEVVNDFKSD IRLPRRHKRN GVSRAAKLWP NARIPYAISP HYSPHERALL AKAVKQYHEK 120
  121 TCIRFVPRQT GEPDYLFIGK VDGCFSEVGR TSGVQVLSLD NGCMEYATII HEMMHVVGFY 180
  181 HEHERWDRDN FIDIIWQNID RGALDQFGKV DLSKTSYYGQ PYDYKSILHY DSLAFSKNGF 240
  241 PTMLPKVKSA TIGNARDFSD VDISKINRMY NCPVEKSVTA PFARARHVPI YSPQYHKYED 300
  301 RPKIPLRSFD MQQGPINPPM AQIPSQSLVV SSSSGRVNYN SNKPSSQCED RITVCWWTAD 360
  361 RCRSPAIYQV MSSLCPKTCK FC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..273] PSI-BLAST 36.39794 STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
    2 View Details [274..382] MSA 16.191997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  4.1917763812737 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  3.85190688399485 bayes_pls_golite062009
  • metallopeptidase activity
    		•  3.22757426039234 bayes_pls_golite062009
  • endopeptidase activity
    		•  2.98133341931091 bayes_pls_golite062009
  • hydrolase activity
    		•  2.78513171530601 bayes_pls_golite062009
  • metalloendopeptidase activity
    		•  2.54952091441017 bayes_pls_golite062009
  • transporter activity
    		•  1.28982382930122 bayes_pls_golite062009
  • binding
    		•  1.14857991858078 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.0688261398267 bayes_pls_golite062009
  • catalytic activity
    		•  0.891187593353827 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.798767221679673 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.543737159152136 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.492456025063956 bayes_pls_golite062009
  • protein binding
    		•  0.430901196209551 bayes_pls_golite062009
  • signal transducer activity
    		•  0.430096231919693 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.430096231919693 bayes_pls_golite062009
  • receptor binding
    		•  0.26922218944514 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.241890854867053 bayes_pls_golite062009
  • receptor activity
    		•  0.233571796352905 bayes_pls_golite062009
  • protein complex binding
    		•  0.171282539150091 bayes_pls_golite062009
  • integrin binding
    		•  0.0945964646680701 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.0544613856966465 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.00533877867882504 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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