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View Structure Prediction Details

Protein: nas-7
Organism: Caenorhabditis elegans
Length: 382 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-7.

Description E-value Query
Range
Subject
Range
gi|187028969, gi... - gi|39582363|emb|CAE67612.1| Hypothetical protein CBG13159 [Caenorhabditis briggsae], gi|187028969|em...
277.0 [0..1] [382..1]

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Predicted Domain #1
Region A:
Residues: [1-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLPWIITIV TVIPATLGHR NRVQDDEMLV ISDSTDSLNL EDFEFADKLT REELFGKHIP  60
   61 VEVVNDFKSD IRLPRRHKRN GVSRAAKLWP NARIPYAISP HYSPHERALL AKAVKQYHEK 120
  121 TCIRFVPRQT GEPDYLFIGK VDGCFSEVGR TSGVQVLSLD NGCMEYATII HEMMHVVGFY 180
  181 HEHERWDRDN FIDIIWQNID RGALDQFGKV DLSKTSYYGQ PYDYKSILHY DSLAFSKNGF 240
  241 PTMLPKVKSA TIGNARDFSD VDISKINRMY NCP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.39794
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.1917763812737 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.85190688399485 bayes_pls_golite062009
metallopeptidase activity 3.22757426039234 bayes_pls_golite062009
endopeptidase activity 2.98133341931091 bayes_pls_golite062009
hydrolase activity 2.78513171530601 bayes_pls_golite062009
metalloendopeptidase activity 2.54952091441017 bayes_pls_golite062009
transporter activity 1.28982382930122 bayes_pls_golite062009
binding 1.14857991858078 bayes_pls_golite062009
transmembrane transporter activity 1.0688261398267 bayes_pls_golite062009
catalytic activity 0.891187593353827 bayes_pls_golite062009
substrate-specific transporter activity 0.798767221679673 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.543737159152136 bayes_pls_golite062009
exopeptidase activity 0.492456025063956 bayes_pls_golite062009
protein binding 0.430901196209551 bayes_pls_golite062009
signal transducer activity 0.430096231919693 bayes_pls_golite062009
molecular transducer activity 0.430096231919693 bayes_pls_golite062009
receptor binding 0.26922218944514 bayes_pls_golite062009
ion transmembrane transporter activity 0.241890854867053 bayes_pls_golite062009
receptor activity 0.233571796352905 bayes_pls_golite062009
protein complex binding 0.171282539150091 bayes_pls_golite062009
integrin binding 0.0945964646680701 bayes_pls_golite062009
transmembrane receptor activity 0.0544613856966465 bayes_pls_golite062009
aminopeptidase activity 0.00533877867882504 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [274-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEKSVTAPFA RARHVPIYSP QYHKYEDRPK IPLRSFDMQQ GPINPPMAQI PSQSLVVSSS  60
   61 SGRVNYNSNK PSSQCEDRIT VCWWTADRCR SPAIYQVMSS LCPKTCKFC

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle