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Protein Overview: set-6

General Information:
Name(s) found: set-6 / CE31454 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00008206 locus:set-6 status:Partially_confirmed UniProt:O17679 protein_id:CAB03974.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 708 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: chromatin modification [IEALink to PubMed article]
    Molecular Function: histone-lysine N-methyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERSRTGGSS TYSMSTANVP IITISDDDDE LTIWEEPRKS PISSNSYSDE RNHSLSSTSN  60
   61 SSVERSIIIT ISDDESEATE RNQQEVVDRA ISNNLTEKRR RSVESFHRLH SKERKLEVKS 120
  121 RKKSRTSSSS MEASTSCTFP ARQTKTKRHK RKTYSTISSF APHHSTICAE LRNVNPARIA 180
  181 DFRHPSIFEY SDMSLNERRE HWKKEMKVIK KHNDIRLMHE EAVRFDDIIE LDPTLNGYYR 240
  241 RFMGAEQSTR ALFMAVRCLA TFGRNFYEEP ERDHGEEEIP EELDRYFEKL IYVAPRTRIR 300
  301 ITDDIHLSND THRIPVYTDA KGETLKTVKI PNPLLYDHII NNMVDKVKEP LLYEAIKIAG 360
  361 SSENVIRCKC CSQDPVVNCF DNKDCPCFIA NQFLQSRNKT TDTNEKLKFH TFQPLMYNDG 420
  421 NPTYYNTVGF ACSPKCACKG ACTNNATYLI QKKLYSIEIY RADPQIGFGI RSTLFIPAGT 480
  481 PIIEYCGELV DGERLHSSLE NYSYQLTDCE GDKHLYNLLR EKYKNNPEYY DVLDELSKHH 540
  541 FHLDAKMQGS VGRFANHSCT PNMEPLRLFK EGFTPANMRM IFFTLKDIFP GEPLTLDYGS 600
  601 EYKVFRRQRC LCRTFACRSG PHYEKFSNLD GKLIASCFVR LHHASRIRYS VDLQLIERFY 660
  661 SVGKVEEVRV DPCVSFSKYN LKWRRQLSTA TCERLENVIE IELSDEDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..243] PSI-BLAST 13.69897 Initiation factor eIF2 gamma subunit, domain II; Initiation factor eIF2 gamma subunit; Initiation factor eIF2 gamma subunit, N-terminal (G) domain
    2 View Details [244..606] PSI-BLAST 51.045757 No description for 2igqA was found.
    3 View Details [607..708] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.51683451033161 bayes_pls_golite062009
  • DNA binding
    		•  2.12258000781149 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09345198747025 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  1.56210491977805 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  1.56210491977805 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.2935968641033 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.2935353851804 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.29138695385133 bayes_pls_golite062009
  • nucleotide binding
    		•  1.28669586915546 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.23094623498843 bayes_pls_golite062009
  • motor activity
    		•  1.14667913749579 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.06255786387629 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • ATP binding
    		•  0.98146619596929 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.949788783884952 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.931486373329219 bayes_pls_golite062009
  • transcription factor activity
    		•  0.887108427603557 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  0.876296121718575 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.862685397469217 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.75415390146713 bayes_pls_golite062009
  • helicase activity
    		•  0.6191010101321 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.60036517876321 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.500462538667228 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.41398614759796 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  0.353804743424317 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.268787661420613 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.208665086324262 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.18426050934025 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.176241137083092 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.147579541298736 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  0.146753696170734 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.14606996093053 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.133017653323467 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.13050483816765 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.113504049290503 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.111293884322157 bayes_pls_golite062009
  • kinase activity
    		•  0.0980017568205789 bayes_pls_golite062009
  • protein kinase activity
    		•  0.0364322017534667 bayes_pls_golite062009
  • actin binding
    		•  0.00482938540552702 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  0.00156323320804219 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  0.00156323320804219 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  0.00156323320804219 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle