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View Structure Prediction Details

Protein: set-6
Organism: Caenorhabditis elegans
Length: 708 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for set-6.

Description E-value Query
Range
Subject
Range
gi|91077470 - gi|91077470|ref|XP_975868.1| PREDICTED: similar to heterochromatin protein isoform 2 [Tribolium cast...
333.0 [0..42] [634..13]

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Predicted Domain #1
Region A:
Residues: [1-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERSRTGGSS TYSMSTANVP IITISDDDDE LTIWEEPRKS PISSNSYSDE RNHSLSSTSN  60
   61 SSVERSIIIT ISDDESEATE RNQQEVVDRA ISNNLTEKRR RSVESFHRLH SKERKLEVKS 120
  121 RKKSRTSSSS MEASTSCTFP ARQTKTKRHK RKTYSTISSF APHHSTICAE LRNVNPARIA 180
  181 DFRHPSIFEY SDMSLNERRE HWKKEMKVIK KHNDIRLMHE EAVRFDDIIE LDPTLNGYYR 240
  241 RFM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1kjzA
Description: Initiation factor eIF2 gamma subunit, domain II; Initiation factor eIF2 gamma subunit; Initiation factor eIF2 gamma subunit, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.64537357529343 bayes_pls_golite062009
nucleic acid binding 2.51683451033161 bayes_pls_golite062009
DNA binding 2.12258000781149 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
lysine N-acetyltransferase activity 1.56210491977805 bayes_pls_golite062009
histone acetyltransferase activity 1.56210491977805 bayes_pls_golite062009
purine ribonucleotide binding 1.2935968641033 bayes_pls_golite062009
ribonucleotide binding 1.2935353851804 bayes_pls_golite062009
purine nucleotide binding 1.29138695385133 bayes_pls_golite062009
nucleotide binding 1.28669586915546 bayes_pls_golite062009
DNA-dependent ATPase activity 1.23094623498843 bayes_pls_golite062009
motor activity 1.14667913749579 bayes_pls_golite062009
histone methyltransferase activity 1.06255786387629 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
ATP binding 0.98146619596929 bayes_pls_golite062009
adenyl ribonucleotide binding 0.949788783884952 bayes_pls_golite062009
adenyl nucleotide binding 0.931486373329219 bayes_pls_golite062009
transcription factor activity 0.887108427603557 bayes_pls_golite062009
protein methyltransferase activity 0.876296121718575 bayes_pls_golite062009
transcription repressor activity 0.862685397469217 bayes_pls_golite062009
DNA helicase activity 0.75415390146713 bayes_pls_golite062009
helicase activity 0.6191010101321 bayes_pls_golite062009
microtubule motor activity 0.60036517876321 bayes_pls_golite062009
cytoskeletal protein binding 0.500462538667228 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.41398614759796 bayes_pls_golite062009
N-acetyltransferase activity 0.353804743424317 bayes_pls_golite062009
ATP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.268787661420613 bayes_pls_golite062009
structural constituent of ribosome 0.208665086324262 bayes_pls_golite062009
RNA helicase activity 0.18426050934025 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.176241137083092 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.147579541298736 bayes_pls_golite062009
N-acyltransferase activity 0.146753696170734 bayes_pls_golite062009
RNA-dependent ATPase activity 0.14606996093053 bayes_pls_golite062009
pyrophosphatase activity 0.133017653323467 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.13050483816765 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.113504049290503 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.111293884322157 bayes_pls_golite062009
kinase activity 0.0980017568205789 bayes_pls_golite062009
protein kinase activity 0.0364322017534667 bayes_pls_golite062009
actin binding 0.00482938540552702 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 0.00156323320804219 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 0.00156323320804219 bayes_pls_golite062009
lysine N-methyltransferase activity 0.00156323320804219 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [244-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAEQSTRALF MAVRCLATFG RNFYEEPERD HGEEEIPEEL DRYFEKLIYV APRTRIRITD  60
   61 DIHLSNDTHR IPVYTDAKGE TLKTVKIPNP LLYDHIINNM VDKVKEPLLY EAIKIAGSSE 120
  121 NVIRCKCCSQ DPVVNCFDNK DCPCFIANQF LQSRNKTTDT NEKLKFHTFQ PLMYNDGNPT 180
  181 YYNTVGFACS PKCACKGACT NNATYLIQKK LYSIEIYRAD PQIGFGIRST LFIPAGTPII 240
  241 EYCGELVDGE RLHSSLENYS YQLTDCEGDK HLYNLLREKY KNNPEYYDVL DELSKHHFHL 300
  301 DAKMQGSVGR FANHSCTPNM EPLRLFKEGF TPANMRMIFF TLKDIFPGEP LTLDYGSEYK 360
  361 VFR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.045757
Match: 2igqA
Description: No description for 2igqA was found.

Predicted Domain #3
Region A:
Residues: [607-708]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQRCLCRTFA CRSGPHYEKF SNLDGKLIAS CFVRLHHASR IRYSVDLQLI ERFYSVGKVE  60
   61 EVRVDPCVSF SKYNLKWRRQ LSTATCERLE NVIEIELSDE DS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle