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Protein Overview: CE30696

General Information:
Name(s) found: CE30696 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00020839 locus:usp-5 Ubiquitin carboxyl-terminal hydrolase status:Confirmed UniProt:P91502 protein_id:CCD72002.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 789 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    ubiquitin-dependent protein catabolic process [IEALink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    ubiquitin thiolesterase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVETAVRSA VDAGAFIRPT FDQKIFKDQC AYCFKDPHGK DGLYISLKNY HAFCREHAEI  60
   61 YGTTSGNTLF VQFESTKKII EERTDGEPTS KMTKLTIDSD PKFEFEDKYC VVVHPEYSQQ 120
  121 VKNVQNLPEI AEAIAQIANT TSAERLSLLS STSNAWDAEI KLITKHQNLE QQDNGKHLAL 180
  181 TGWTCEVEGC GLNDNLWLNL TDGAVRCGRS QFLSDGKKTN GNGHMQDYFD STRFPLVVKL 240
  241 GTISSNLELI DVYSYDEDDA VIDPNLEKHL KHFGLDPTKM EKTAKSTMEM ELDMNEKWEW 300
  301 SKCTEDGLLL EPIFGPGYTG LVNTGSSCYM NSVLQALVTV DSFQTRYGEQ GLETLVNCPL 360
  361 DKLHNDFNAQ FSKVVRAMLS GDYSSEMDPT NNHIKPLQFK RVAAGNHRDF STSKQQDVEE 420
  421 YIRFLFEKIA ENSRTEVIDP TDSFKFKAIN RFEDRGTRRV RYTDQEEMLI RLPISGDLLR 480
  481 PIPDTENRYS VDMKAAIHAY FDVQKIDDYI SPITGEPKGA TNTISMKTFP DYLFFQVSKF 540
  541 AYNVDGTQKK LDMELEIEEE LDLSGYRGHG KLEHEIALPD EEPTAPRTTP DIPASVRFVA 600
  601 GELMLMGFCE NACYRAAYYS NGNVEIASNW LMEHMDDSDI NDLFVIPSGT PSARGEVDPN 660
  661 LVASIVEMGF SNHQAKYALK QVPTVAEAVE WLFANMDSIP VESAAVGLSS DAPEPSVTES 720
  721 ATQKTFKDGG EKYKLIGMIS HMGSRPDSGH YVAHMLKEGK WVLFNDEKVA LSQDPPKKLA 780
  781 YVYLYKRIA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..99] FFAS03 1.67 No description for 2idaA was found.
    2 View Details [100..300] PSI-BLAST 20.0 No description for 2g43A was found.
    3 View Details [301..789] FFAS03 9.15 Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces cerevisiae at 1.74 A resolution

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  4.67600289365776 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  4.4180348594722 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  3.7630891050221 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  3.26583764896015 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  3.19070920649427 bayes_pls_golite062009
  • binding
    		•  2.70912934275371 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  2.63153614400976 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.33467249420642 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.16379604127358 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  2.02075518391878 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.8142438325367 bayes_pls_golite062009
  • peptidase activity
    		•  1.63698757480466 bayes_pls_golite062009
  • hydrolase activity
    		•  1.63137875153947 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.60954084225588 bayes_pls_golite062009
  • DNA binding
    		•  1.58326992587523 bayes_pls_golite062009
  • protein binding
    		•  1.48593945455888 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.29640196277559 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  0.912215968653949 bayes_pls_golite062009
  • ligase activity
    		•  0.905192840625194 bayes_pls_golite062009
  • transcription factor activity
    		•  0.86907979176353 bayes_pls_golite062009
  • transcription factor binding
    		•  0.852951089928981 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.616289233269298 bayes_pls_golite062009
  • catalytic activity
    		•  0.168711389690753 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.102158909244177 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • cysteine-type peptidase activity
    		•  6.0242292884398 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  5.90858078304578 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  5.44933450089323 bayes_pls_golite062009
  • peptidase activity
    		•  4.48757818618372 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.1155744959349 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  3.74006277974234 bayes_pls_golite062009
  • hydrolase activity
    		•  3.55540874211118 bayes_pls_golite062009
  • endopeptidase activity
    		•  3.08933587387084 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  2.64375377835891 bayes_pls_golite062009
  • SUMO-specific protease activity
    		•  2.21040757005122 bayes_pls_golite062009
  • binding
    		•  1.92915144283226 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.63311616646381 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.57189830536041 bayes_pls_golite062009
  • DNA binding
    		•  1.53025117349636 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  1.47306695258161 bayes_pls_golite062009
  • catalytic activity
    		•  0.995453662223124 bayes_pls_golite062009
  • transcription factor activity
    		•  0.848050636661084 bayes_pls_golite062009
  • protein binding
    		•  0.834719536847984 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.477566616141912 bayes_pls_golite062009
  • NEDD8-specific protease activity
    		•  0.286821085697906 bayes_pls_golite062009
  • transferase activity
    		•  0.11895486539858 bayes_pls_golite062009
  • kininogen binding
    		•  0.0480015503126463 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle