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Protein Overview: CE28160

General Information:
Name(s) found: CE28160 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00022610 status:Confirmed UniProt:O44183 protein_id:CCD68240.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 625 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: leukotriene biosynthetic process [IEALink to PubMed article]
    proteolysis [IEALink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    actin binding [IEALink to PubMed article]
    leukotriene-A4 hydrolase activity [IEALink to PubMed article]
    membrane alanyl aminopeptidase activity [IEALink to PubMed article]
    metallopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCQLHNFRPK RDPCSAANIN EITVEHTAIK WTVSFQLKMI IGQATLRCRC LTDATKLVLD  60
   61 VRDLSIRSVS INGVDCDFRI APNVYTFFGS KMSVYLPPQF QKAGTILQVT VAYGTSPDAT 120
  121 ALQWMKKEQT ADKRMPYLFS QCQAIHARSI VPCMDTPSVK STYEAEVTVP TGMTCLMSAI 180
  181 GQGSKGDDDT TTFFYKQPVA IPSYLIAIVV GCLEKRDISD RCAVWAEPSV VDKAHWEFAE 240
  241 TEDILASAEE IAGKYIWGRY DMVCLPPSFP FGGMENPCLT FLTPTLIAGD RSLVSVIAHE 300
  301 IAHSWSGNLV TNSSWEHFWL NEGFTMFIER KICGRLVSED YRQFMAFNGW TNSLIPAVYE 360
  361 QFTPTHQFTK LIQDHTNVDP DVAFSCVPYE KGSALLFYLE QKLGGSEIFE AYLKDYLKTF 420
  421 AHQAIDSWQW KDHLYKYFAD QKEVLDTVNF DLWFNGVGMP PEKPNYGQSM VEACEVLLKK 480
  481 WLAADESTVG DITSEDYYAM QPLQQIELLS QLWQHDPPIE HYKLDALNKL YKLNDSQNSE 540
  541 LLLNWLRLCI KSKWEECIPK ALDFVNSQGR LKFCRPIYRD LAQWPIANKK ARDVYLKGRS 600
  601 QMHPITAEMI AKDLHIRHST HTVCF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..625] PSI-BLAST 129.0 Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  5.33358263548929 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.99457783001146 bayes_pls_golite062009
  • endopeptidase activity
    		•  4.16532996235931 bayes_pls_golite062009
  • metallopeptidase activity
    		•  3.94798058866011 bayes_pls_golite062009
  • metalloendopeptidase activity
    		•  3.05952802601629 bayes_pls_golite062009
  • hydrolase activity
    		•  2.55673800115122 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.64539435934931 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.63993432278466 bayes_pls_golite062009
  • binding
    		•  1.56078736789756 bayes_pls_golite062009
  • receptor binding
    		•  1.15741823528763 bayes_pls_golite062009
  • catalytic activity
    		•  0.891187593353827 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.686302227492162 bayes_pls_golite062009
  • DNA binding
    		•  0.564067563573999 bayes_pls_golite062009
  • RNA binding
    		•  0.40024158562931 bayes_pls_golite062009
  • serine hydrolase activity
    		•  0.393080846858665 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  0.374597710524442 bayes_pls_golite062009
  • integrin binding
    		•  0.35834172649072 bayes_pls_golite062009
  • growth factor activity
    		•  0.352343150818166 bayes_pls_golite062009
  • protein binding
    		•  0.278366242068789 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  0.252655558968584 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.21808506596674 bayes_pls_golite062009
  • protein complex binding
    		•  0.134132828555441 bayes_pls_golite062009
  • transcription factor activity
    		•  0.012234449355649 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle