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Protein Overview: tufm-1

General Information:
Name(s) found: tufm-1 / CE27322 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00007000 locus:tufm-1 status:Confirmed UniProt:G5ECM6 protein_id:CCD73874.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 496 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: selenocysteine incorporation [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    translational elongation [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: GTP binding [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]
    translation elongation factor activity [IEALink to PubMed article]
    GTPase activity [IEALink to PubMed article]
    transferase activity, transferring phosphorus-containing groups [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQILNLLSRN VGVFKTVTLC EQKMQQVSLM QARHLAVPGG KAVFKRDKPH LNVGTIGHVD  60
   61 HGKTTLTSAI TKILATSKGA KYRKYEDIDN APEEKARGIT INAFHLEYET AKRHYAHIDC 120
  121 PGHADYIKNM ITGAAQMEGA ILVVAATDGP MPQTREHLLL ARQVGVPLDN IVVFMNKVDE 180
  181 VPDAETRELV EMDIREQLNE FGYPGDTCPV IFGSALCALE GKQPEIGEEA VKQLLEVLDN 240
  241 KFVIPERKVN EEPMFAAEHV YSIVGRGTVI TGKLERGILK RGDKIEIVGG TKDGTTVKSV 300
  301 ISGLESFRKT VDQAEPGDQL GVLLRGLGPK DVRRGCVLLP QGHKHKVTDK VKAQLYVLKE 360
  361 SEGGAKTPIA NYFSEHVFSL TWDSGASVRI IGKDFVMPGE SAEVELSLNS QMFIEPQQRF 420
  421 TIRKGAKTIG TGVFTDVLPP LTNDEKDPKS KKKLMKAEME RLGFNPYGDM VEKRLKPDFS 480
  481 NSPKDNPAAK AFEGQP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..496] PSI-BLAST 98.0 Crystal Structure of Bos taurus mitochondrial Elongation Factor Tu/Ts Complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation elongation factor activity
    		•  8.90683166637832 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  4.8378725567094 bayes_pls_golite062009
  • translation regulator activity
    		•  4.79814772079421 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  4.56509805974548 bayes_pls_golite062009
  • structural molecule activity
    		•  3.58406348799895 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.50494515048649 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.39629638016861 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.39600931083427 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.36051733655256 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.35906629925754 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.35679406876731 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.24901251684901 bayes_pls_golite062009
  • actin filament binding
    		•  2.1683792904715 bayes_pls_golite062009
  • motor activity
    		•  2.11140484670646 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.65609907941094 bayes_pls_golite062009
  • hydrolase activity
    		•  1.57549510726226 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.49633029954726 bayes_pls_golite062009
  • actin binding
    		•  1.42666717383185 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.40488517180956 bayes_pls_golite062009
  • microfilament motor activity
    		•  1.33993901826495 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.3182108176243 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • DNA binding
    		•  0.967303417236485 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.76547843267689 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.748437190903548 bayes_pls_golite062009
  • peptidyltransferase activity
    		•  0.705667095586631 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.704934361725919 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.60036517876321 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  0.353150780751661 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.296406132096546 bayes_pls_golite062009
  • GTP binding
    		•  0.295705904888768 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.29028316917561 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.282397764628576 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  0.12168417344278 bayes_pls_golite062009
  • RNA binding
    		•  0.0693163519626152 bayes_pls_golite062009
  • protein transporter activity
    		•  0.0397092337273124 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.0378638259240902 bayes_pls_golite062009
  • peptide transporter activity
    		•  0.0135927378126404 bayes_pls_golite062009
  • signal sequence binding
    		•  6.53725193420218E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle