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View Structure Prediction Details

Protein: tufm-1
Organism: Caenorhabditis elegans
Length: 496 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tufm-1.

Description E-value Query
Range
Subject
Range
gi|56377788 - gi|56377788|dbj|BAD74118.1| elongation factor-1 alpha (EF-1alpha) [Pelodiscus sinensis]
439.0 [0..44] [458..1]

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Predicted Domain #1
Region A:
Residues: [1-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQILNLLSRN VGVFKTVTLC EQKMQQVSLM QARHLAVPGG KAVFKRDKPH LNVGTIGHVD  60
   61 HGKTTLTSAI TKILATSKGA KYRKYEDIDN APEEKARGIT INAFHLEYET AKRHYAHIDC 120
  121 PGHADYIKNM ITGAAQMEGA ILVVAATDGP MPQTREHLLL ARQVGVPLDN IVVFMNKVDE 180
  181 VPDAETRELV EMDIREQLNE FGYPGDTCPV IFGSALCALE GKQPEIGEEA VKQLLEVLDN 240
  241 KFVIPERKVN EEPMFAAEHV YSIVGRGTVI TGKLERGILK RGDKIEIVGG TKDGTTVKSV 300
  301 ISGLESFRKT VDQAEPGDQL GVLLRGLGPK DVRRGCVLLP QGHKHKVTDK VKAQLYVLKE 360
  361 SEGGAKTPIA NYFSEHVFSL TWDSGASVRI IGKDFVMPGE SAEVELSLNS QMFIEPQQRF 420
  421 TIRKGAKTIG TGVFTDVLPP LTNDEKDPKS KKKLMKAEME RLGFNPYGDM VEKRLKPDFS 480
  481 NSPKDNPAAK AFEGQP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.0
Match: 1xb2A
Description: Crystal Structure of Bos taurus mitochondrial Elongation Factor Tu/Ts Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation elongation factor activity 8.90683166637832 bayes_pls_golite062009
translation factor activity, nucleic acid binding 4.8378725567094 bayes_pls_golite062009
translation regulator activity 4.79814772079421 bayes_pls_golite062009
structural constituent of ribosome 4.56509805974548 bayes_pls_golite062009
structural molecule activity 3.58406348799895 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
primary active transmembrane transporter activity 2.39629638016861 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.39600931083427 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.36051733655256 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.35906629925754 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.35679406876731 bayes_pls_golite062009
ATPase activity, coupled 2.24901251684901 bayes_pls_golite062009
actin filament binding 2.1683792904715 bayes_pls_golite062009
motor activity 2.11140484670646 bayes_pls_golite062009
substrate-specific transporter activity 1.65609907941094 bayes_pls_golite062009
hydrolase activity 1.57549510726226 bayes_pls_golite062009
nucleic acid binding 1.49633029954726 bayes_pls_golite062009
actin binding 1.42666717383185 bayes_pls_golite062009
cytoskeletal protein binding 1.40488517180956 bayes_pls_golite062009
microfilament motor activity 1.33993901826495 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.3182108176243 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
DNA binding 0.967303417236485 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
RNA helicase activity 0.76547843267689 bayes_pls_golite062009
transcription regulator activity 0.748437190903548 bayes_pls_golite062009
peptidyltransferase activity 0.705667095586631 bayes_pls_golite062009
ion transmembrane transporter activity 0.704934361725919 bayes_pls_golite062009
microtubule motor activity 0.60036517876321 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
anion transmembrane-transporting ATPase activity 0.353150780751661 bayes_pls_golite062009
guanyl nucleotide binding 0.296406132096546 bayes_pls_golite062009
GTP binding 0.295705904888768 bayes_pls_golite062009
guanyl ribonucleotide binding 0.29028316917561 bayes_pls_golite062009
cation transmembrane transporter activity 0.282397764628576 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 0.12168417344278 bayes_pls_golite062009
RNA binding 0.0693163519626152 bayes_pls_golite062009
protein transporter activity 0.0397092337273124 bayes_pls_golite062009
protein transmembrane transporter activity 0.0378638259240902 bayes_pls_golite062009
peptide transporter activity 0.0135927378126404 bayes_pls_golite062009
signal sequence binding 6.53725193420218E-4 bayes_pls_golite062009

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Created and Maintained by: Michael Riffle