YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: egl-10

General Information:
Name(s) found: egl-10 / CE24928 [WormBase]
Description(s) found:
Found 21 descriptions.
SHOW ALL
  • WBGene00001179 locus:egl-10 Regulator of G-protein signaling egl-10 status:Confirmed UniProt:P49809 protein_id:CAA99844.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 555 amino acids

    Gene Ontology:
    Cellular Component: heterotrimeric G-protein complex [IEALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    neuron projection [IDALink to PubMed article]
    Biological Process: regulation of oviposition [IMPLink to PubMed article]
    G-protein coupled receptor protein signaling pathway [IEALink to PubMed article]
    dopamine receptor signaling pathway [IMPLink to PubMed article]
    feeding behavior [IMPLink to PubMed article]
    regulation of G-protein coupled receptor protein signaling pathway [IGILink to PubMed article][ISSLink to PubMed article]
    rhythmic behavior [IMPLink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: regulator of G-protein signaling activity [IGILink to PubMed article][ISSLink to PubMed article]
    signal transducer activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALPRLRVNA SNEERLVHPN HMVYRKMEML VNQMLDAEAG VPIKTVKSFL SKVPSVFTGQ  60
   61 DLIGWIMKNL EMTDLSDALH LAHLIASHGY LFQIDDHVLT VKNDGTFYRF QTPYFWPSNC 120
  121 WDPENTDYAV YLCKRTMQNK AHLELEDFEA ENLAKLQKMF SRKWEFVFMQ AEAQYKVDKK 180
  181 RDRQERQILD SQERAFWDVH RPVPGCVNTT EVDFRKLSRS GRPKYSSGGH AALAASTSGI 240
  241 GCTQYSQSVA AAHASLPSTS NGSATSPRKN DQEPSTSSGG ESPSTSSAAA GTATTSAPST 300
  301 STPPVTTITA TINAGSFRNN YYTRPGLRRC TQVQDTLKLE IVQLNSRLSK NVLRTSKVVE 360
  361 NYLAYYEQRR VFDPLLTPPG SQADPFQSQP NPWINDTVDF WQHDKITGDI QTRRLKLWED 420
  421 SFEELLADSL GRETLQKFLD KEYSGENLRF WWEVQKLRKC SSRMVPVMVT EIYNEFIDTN 480
  481 AATSPVNVDC KVMEVTEDNL KNPNRWSFDE AADHIYCLMK NDSYQRFLRS EIYKDLVLQS 540
  541 RKKVSLNCSF SIFAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..120] PSI-BLAST 27.09691 Segment polarity protein Dishevelled-1
    2 View Details [121..206] MSA 1.16198 View MSA. No confident structure predictions are available.
    3 View Details [207..314] FFAS03 1.55 The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer
    4 View Details [315..555] PSI-BLAST 37.09691 Regulator of G-protein signalling 4, RGS4

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.62737887048829 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.24995934604055 bayes_pls_golite062009
  • DNA binding
    		•  1.98873150682164 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.88100667301756 bayes_pls_golite062009
  • transcription factor activity
    		•  1.38071536959278 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.71352470280335 bayes_pls_golite062009
  • transcription activator activity
    		•  0.637473513125737 bayes_pls_golite062009
  • protein binding
    		•  0.498124455750984 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.00364315876158 bayes_pls_golite062009
  • protein binding
    		•  0.151788856727459 bayes_pls_golite062009
  • GTPase activity
    		•  0.00398672503585712 bayes_pls_golite062009
    4
    Term Confidence Notes
  • GTPase regulator activity
    		•  1.63734012092956 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.61106381835327 bayes_pls_golite062009
  • GTPase activator activity
    		•  1.58095588540049 bayes_pls_golite062009
  • binding
    		•  1.45102555794319 bayes_pls_golite062009
  • enzyme activator activity
    		•  1.34819535045475 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.22696878792766 bayes_pls_golite062009
  • protein binding
    		•  1.09246587992573 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle