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Protein Overview: CE24840

General Information:
Name(s) found: CE24840 [WormBase]
Description(s) found:
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  • WBGene00016589 status:Confirmed UniProt:G5EFT4 protein_id:CAM36352.1 [WormBase]
  • gi|71984339|ref|NP_001023056.1| hypothetical protein C42C1.11 [Caenorhabditis elegans] [NCBI NR]
  • gi|3859874|gb|AAC72891.1| aminopeptidase-1 [Caenorhabditis elegans] [NCBI NR]
  • gi|3372864|gb|AAC70927.1| aminopeptidase-1 [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_502335.1| aminopeptidase 1, structurally related to mammalian leukotriene A4 hydrolases (68.2 kD) (4N45) [Caenorhabditis elegans] [NCBI NR]
  • gi|14702093|gb|AAB97552.2| Hypothetical protein C42C1.11a [Caenorhabditis elegans] [NCBI NR]
  • gi|126468479|emb|CAM36352.1| C. elegans protein C42C1.11a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE24840 WBGene00016589 peptidase status:Confirmed TR:O44969 protein_id:AAB97552.2 [wormpep150.fasta]
  • 24840 WBGene00016589 peptidase status:Confirmed TR:O44969 protein_id:AAB97552.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • aminopeptidase 1, structurally related to mammalian leukotriene A4 hydrolases (68.2 kD) (4N45) [Caenorhabditis elegans]gi|14702093|gb|AAB97552.2| Hypothetical protein C42C1.11a [Caenorhabditis elegans]gi|3859874|gb|AAC72891.1| aminopeptidase-1 [Caenorha [nrdb_11152004_Chlamydomonas]
  • peptidase status:Confirmed TR:O44969 protein_id:AAB97552.2 [wormpep115.fasta.reversed]
  • CE24840 peptidase status:Confirmed TR:O44969 protein_id:AAB97552.2 [wormpep80.hongbin]
  • CE24840 WBGene00016589 peptidase status:Confirmed UniProt:Q7KPI8_CAEEL protein_id:CAM36352.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE24840 WBGene00016589 peptidase status:Confirmed UniProt:Q7KPI8_CAEEL protein_id:CAM36352.1| [wormORF-contam.fasta]
  • aminopeptidase-1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C42C1.11a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • C42C1.11a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE24840 WBGene00016589 peptidase status:Confirmed TR:Q7KPI8 protein_id:CAM36352.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE24840 WBGene00016589 peptidase status:Confirmed UniProt:Q7KPI8 protein_id:CAM36352.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE24840 WBGene00016589 peptidase status:Confirmed UniProt:G5EFT4 protein_id:CAM36352.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE24840 WBGene00016589 status:Confirmed UniProt:G5EFT4 protein_id:CAM36352.1 [wormpep246-ecoli-contam.fasta]
  • Aminopeptidase-1 OS=Caenorhabditis elegans GN=AP-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 609 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: leukotriene biosynthetic process [IEALink to PubMed article]
    proteolysis [IEALink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    leukotriene-A4 hydrolase activity [IEALink to PubMed article]
    membrane alanyl aminopeptidase activity [IEALink to PubMed article]
    metallopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPHPRDPS TAANYEQVTV SHYALKWKVD FEKKHIAGDV SITLDVKQDT ERIVLDTRDL  60
   61 SVQSVALNLN GEPKKAGFTL EDNQALGQKL VITTESLKSG DRPVLEIKYE SSNNAAALQF 120
  121 LTAEQTTDRV APYLFSQCQA INARSIVPCM DTPSVKSTYE AEVCVPIGLT CLMSAIGQGS 180
  181 TPSECGKRTI FSFKQPVSIP SYLLAIVVGH LERKEISERC AVWAEPSQAE ASFYEFAETE 240
  241 KILKVAEDVA GPYVWGRYDL VVLPATFPFG GMENPCLTFI TPTLLAGDRS LVNVIAHEIS 300
  301 HSWTGNLVTN FSWEHFWLNE GFTVFLERKI HGKMYGELER QFESESGYEE ALVRTVNDVF 360
  361 GPDHEYTKLV QNLGNADPDD AFSSVPYEKG SALLFTIEQA LGDNSRFEQF LRDYIQKYAY 420
  421 KTVSTEEWKE YLYDSFTDKK VILDNIDWNL WLHKAGLPPK PKYDSTPMQA CKDLAAKWTT 480
  481 EGSEAPTDGE VFAKMSNSQK LAVLDAVRVN KTMFGDRMPA LTATYKLDQA KNAELKFSWL 540
  541 MLGLETKWSP IVDASLAFAL AVGRMKYCKP IYRSLFGWSA TRDRAISQFK ANIPNMHPIT 600
  601 VKAIQSLLK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..609] PSI-BLAST 122.0 Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  5.33358263548929 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.99457783001146 bayes_pls_golite062009
  • endopeptidase activity
    		•  4.16532996235931 bayes_pls_golite062009
  • metallopeptidase activity
    		•  3.94798058866011 bayes_pls_golite062009
  • metalloendopeptidase activity
    		•  3.05952802601629 bayes_pls_golite062009
  • hydrolase activity
    		•  2.55673800115122 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.64539435934931 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.63993432278466 bayes_pls_golite062009
  • binding
    		•  1.56078736789756 bayes_pls_golite062009
  • receptor binding
    		•  1.15741823528763 bayes_pls_golite062009
  • catalytic activity
    		•  0.891187593353827 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.686302227492162 bayes_pls_golite062009
  • DNA binding
    		•  0.564067563573999 bayes_pls_golite062009
  • RNA binding
    		•  0.40024158562931 bayes_pls_golite062009
  • serine hydrolase activity
    		•  0.393080846858665 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  0.374597710524442 bayes_pls_golite062009
  • integrin binding
    		•  0.35834172649072 bayes_pls_golite062009
  • growth factor activity
    		•  0.352343150818166 bayes_pls_golite062009
  • protein binding
    		•  0.278366242068789 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  0.252655558968584 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.21808506596674 bayes_pls_golite062009
  • protein complex binding
    		•  0.134132828555441 bayes_pls_golite062009
  • transcription factor activity
    		•  0.012234449355649 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle