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Protein Overview: CE17439

General Information:
Name(s) found: CE17439 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00000487 locus:che-6 cyclic nucleotide-binding protein status:Partially_confirmed UniProt:O61827 protein_id:CCD65345.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 644 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: ion transport [IEALink to PubMed article]
    Molecular Function: ion channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVEKYLEDE ELESFDIYPS GWTICKDILH DSFHRLLYFY VPFNSKYYYI WSFFVSFGVM  60
   61 YNMFAMVIFI FADIKTQYFW NWIFLNVMFD MVFIVDIFVQ SRLTYLHEGE EVKNTKKLRK 120
  121 NYFFQKLKVA NDIFCLLPLD FLLFFDDSMS LVLIRLMDFV QRTQQQTTFP RAFKIILLAV 180
  181 SCIVLFHWNA CLYFLFSLYE GITEESQTEF GFSYYKVFEP VFPTCQAYYD ENCWFGEDID 240
  241 HTLDLDDVRD SYKKEMAEYW KDKHYRWTTG NFSREYSMSI YWSALTITTC GQQPWPSTSS 300
  301 QNSLEVFDTL IGVLVFATII GSWLPTQHKN SPKSEISGVG SVVTQMSQTV NEFRQMMDGI 360
  361 KFYMKYREVN SAIQERALSC FMYLMAHNQL DDEEGILSLL PPRLQANIAA NLHMETLQNI 420
  421 QIFALCESRF MHEVVLLVKQ QVFSPNDYLC RKNEKAKELF IVKKGKLRVI DDDTGEEMGE 480
  481 LTEGATFGEL SIVYVKGNLL GTRRCCSLQS VGFSDIYVLY RDDVSRLLQE FPQEYKTIVM 540
  541 NARNLLHSRG LLETTELGEM CDPSDHEEAD DLVLEEMSVV EQLNRLNGII DGLNGNMNVM 600
  601 ILSFSNSCSY YKQKITGLED TFNQNREQIR SDFKNGLYID FIDY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..330] FFAS03 5.39 Crystal structure of KvAP-33H1 Fv complex
    2 View Details [331..560] PSI-BLAST 28.30103 HCN2J 443-645 in the presence of cGMP
    3 View Details [561..644] PSI-BLAST 27.522879 Catabolite gene activator protein (CAP), C-terminal domain; Catabolite gene activator protein, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cation channel activity
    		•  8.8271544979352 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  8.821528894161 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  8.74133052120115 bayes_pls_golite062009
  • ion channel activity
    		•  8.5319589047463 bayes_pls_golite062009
  • gated channel activity
    		•  8.44554798975713 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  8.43463411234305 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  8.4117395754193 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  8.36000486601638 bayes_pls_golite062009
  • channel activity
    		•  8.32023913192244 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  8.32023913192244 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  8.30986502722514 bayes_pls_golite062009
  • potassium channel activity
    		•  8.23401095904851 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  5.43467612453479 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  5.43467612453479 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.88789838906314 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.80939024913503 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.43208330555032 bayes_pls_golite062009
  • transporter activity
    		•  2.77619896060397 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  2.77094691956851 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.65613366364107 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.60593795082679 bayes_pls_golite062009
    2
    Term Confidence Notes
  • cyclic nucleotide-gated ion channel activity
    		•  10.1422916734545 bayes_pls_golite062009
  • intracellular cyclic nucleotide activated cation channel activity
    		•  10.1422916734545 bayes_pls_golite062009
  • intracellular ligand-gated ion channel activity
    		•  9.72053268940283 bayes_pls_golite062009
  • cation channel activity
    		•  9.48749374439976 bayes_pls_golite062009
  • ion channel activity
    		•  9.4846197809463 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  9.3929063879608 bayes_pls_golite062009
  • channel activity
    		•  9.25176207085973 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  9.25176207085973 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  9.2472549851376 bayes_pls_golite062009
  • intracellular cGMP activated cation channel activity
    		•  9.19973076787954 bayes_pls_golite062009
  • gated channel activity
    		•  9.19042473454294 bayes_pls_golite062009
  • cGMP binding
    		•  7.7575871125398 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  7.41584542512987 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  7.41584542512987 bayes_pls_golite062009
  • cyclic nucleotide binding
    		•  7.37322432929433 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  6.57272328088253 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  6.54930851487319 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.54400173845933 bayes_pls_golite062009
  • GMP binding
    		•  5.49455172024846 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  5.34760703274696 bayes_pls_golite062009
  • potassium channel activity
    		•  5.29889968906368 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  5.1138025954757 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  4.96516802098805 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  4.52895684111035 bayes_pls_golite062009
  • intracellular cAMP activated cation channel activity
    		•  3.95109938608832 bayes_pls_golite062009
  • transporter activity
    		•  3.30740141256752 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.24402760485462 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.22443361822344 bayes_pls_golite062009
  • protein binding
    		•  1.86347494944834 bayes_pls_golite062009
  • signal transducer activity
    		•  1.7487659479534 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.7487659479534 bayes_pls_golite062009
  • binding
    		•  1.59096092728475 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.52941414851886 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.40720858109605 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.33862527414723 bayes_pls_golite062009
  • DNA binding
    		•  1.17942022803543 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.930640481652164 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.910527807644534 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.848189810874263 bayes_pls_golite062009
  • transcription factor activity
    		•  0.720377542376114 bayes_pls_golite062009
  • transcription activator activity
    		•  0.659469524274627 bayes_pls_golite062009
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  4.51306541310201 bayes_pls_golite062009
  • DNA binding
    		•  4.12876602944304 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.12610640813616 bayes_pls_golite062009
  • transcription factor activity
    		•  3.36245551077648 bayes_pls_golite062009
  • binding
    		•  2.88885372623841 bayes_pls_golite062009
  • transcription activator activity
    		•  2.797376139366 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.67296989086846 bayes_pls_golite062009
  • protein binding
    		•  1.80415286835431 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.67982218586786 bayes_pls_golite062009
  • signal transducer activity
    		•  1.42015496657117 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.42015496657117 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.35320462873179 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle