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Protein Overview: ech-4

General Information:
Name(s) found: ech-4 / CE01625 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00001153 locus:ech-4 status:Confirmed UniProt:Q09603 protein_id:CAA86779.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 385 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: metabolic process [IEALink to PubMed article]
    menaquinone biosynthetic process [IEALink to PubMed article]
    Molecular Function: naphthoate synthase activity [IEALink to PubMed article]
    acyl-CoA binding [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRNLTLAAR SVLYNPQVSV RSFSAQADFE KAQKNLKTLK EEPDNDVKLQ LYGLFKQATA  60
   61 GDVQGKRPGM MDFVGRAKYD AWNTLKGQTQ DEARANYAKL VGGLISEEAS AAPEPTGPSI 120
  121 EGLENVDGLS VTREGKVFKI ALNRPKKFNA LTLEMYQGIQ KALEVSNNDK STSITVITAN 180
  181 GSYYCAGNDL TNFKAAAGGT KEQIADMANT AKVIMKDYVN AYINHEKPLI ALINGPAVGI 240
  241 AVTVLGMFDY VIATDKASFH TPFAPLGQSP EGVSSYTFPL IMGSLRASEM LLVCKKISAQ 300
  301 TAKDYGLVNE VVPDAEFQSH AQKTVEAFSQ LPPETLRINK KLLRSLHKEK LLEVNNIEAD 360
  361 QICERWQSKE CHQAIAAFMT KGAKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] PSI-BLAST 23.69897 Solution Structure of RSGI RUH-045, a Human Acyl-CoA Binding Protein
    2 View Details [110..385] PSI-BLAST 50.69897 The crystal structure of human peroxisomal delta3, delta2 enoyl CoA isomerase (PECI)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  4.25084649365698 bayes_pls_golite062009
  • enoyl-CoA hydratase activity
    		•  3.92947460544831 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  3.59076614105466 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  3.4980371783229 bayes_pls_golite062009
  • acetyl-CoA carboxylase activity
    		•  3.34692152434862 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing C=C bonds
    		•  1.97586838275054 bayes_pls_golite062009
  • dodecenoyl-CoA delta-isomerase activity
    		•  1.80820904754223 bayes_pls_golite062009
  • peptidase activity
    		•  1.47343502162051 bayes_pls_golite062009
  • catalytic activity
    		•  1.46154163027498 bayes_pls_golite062009
  • 3-hydroxybutyryl-CoA epimerase activity
    		•  1.31614278936637 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.23984584411791 bayes_pls_golite062009
  • propionyl-CoA carboxylase activity
    		•  1.20853698666984 bayes_pls_golite062009
  • binding
    		•  1.20603792135994 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.15490979946714 bayes_pls_golite062009
  • acyl-CoA binding
    		•  1.11251823193438 bayes_pls_golite062009
  • racemase and epimerase activity, acting on hydroxy acids and derivatives
    		•  1.08284170936757 bayes_pls_golite062009
  • long-chain-3-hydroxyacyl-CoA dehydrogenase activity
    		•  1.03484393216342 bayes_pls_golite062009
  • ligase activity
    		•  0.98581896521131 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.875283244957267 bayes_pls_golite062009
  • long-chain-enoyl-CoA hydratase activity
    		•  0.571617594666499 bayes_pls_golite062009
  • serine hydrolase activity
    		•  0.33742439899675 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  0.317691759858941 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  0.231579308140546 bayes_pls_golite062009
  • hydrolase activity
    		•  0.167287221009063 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.51

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle