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Protein Overview: str2

General Information:
Name(s) found: str2 / SPCC61.01c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • siderophore-iron transporter Str2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 597 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole membrane [IDALink to PubMed article]
    integral to membrane [ICLink to PubMed article]
    Biological Process: cellular iron ion homeostasis [ICLink to PubMed article]
    transmembrane transport [IEA]
    siderophore-iron transport [TASLink to PubMed article]
    iron assimilation by chelation and transport [TASLink to PubMed article]
    Molecular Function: siderophore-iron (ferrioxamine) uptake transmembrane transporter activity [TASLink to PubMed article]
    iron ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTENYGSMEH RKKSFRNNEN LEQQFHPLRE ELDNAGPIND RTSELSLEGV SKAEAIASTW  60
   61 SKRSIIVAYL GLYLLSFASS LEQQTTYSLQ RYATSNFSAH SNLATINLVG NILLAVVRAP 120
  121 MVKAADVFGR SESLSLALGM TVLGYLSLAF SRNIQMFTVA YILYICGQTG LGLLSQLIIA 180
  181 DTSSLLNRGI LSAIPELPYL ATVWIGPVLA QAFHPEKNYG WRLGYGIWAF ILPTVSLPLL 240
  241 ASLFLNQRKA KAAGLYREHH NLINHSTPEK LRLFYLFWQE LDGLGIVLFV SGFTLLLLPF 300
  301 SHSSQVVSPD STILTLFTIT LSIALLVTLC FYDVKYARYP VFALKSLKDR TILGSCVLIF 360
  361 TYFMSYYIFS NFLTSFLQVS YGLSIDMSSL TLNVFVFSMT TTAILSGFLM KRFGRFKMLL 420
  421 MISVPMYVLG ILGIILFGIN DNHYTRPLVL VLILAGMGGG LLTLSAQIAV QSVSSHAKLG 480
  481 MNLTLYLTFS SVGGAFGSAI AGGVWSKRLS SRLLHDLKDH LPVPEIESIF RDLRTALSYP 540
  541 QGTQIRNIIN VAYTATEKDL FHISLVASLF MFAGLVIIRD VPLSTENHDT AVETPSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..474] PSI-BLAST 18.39794 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
    2 View Details [475..597] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • binding
    		•  1.26757615356623 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  1.24023641504332 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle