YRC Public Data Repository - Protein Structure Prediction

Protein:	str2
Organism:	Schizosaccharomyces pombe
Length:	597 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for str2.

Description	E-value	Query Range	Subject Range
gi\|46107656, gi\|... - gi\|46107656\|ref\|XP_380887.1\| hypothetical protein FG00711.1 [Gibberella zeae PH-1], gi\|42547814\|gb\|E...	303.0	[0..1]	[589..1373]
gi\|60467752, gi\|... - gi\|60467752\|gb\|EAL65769.1\| hypothetical protein DDB0191430 [Dictyostelium discoideum], gi\|29500764\|g... gi\|60467752, gi\|... - gi\|66810832\|ref\|XP_639123.1\| major facilitator superfamily transporter [Dictyostelium discoideum AX4...	288.0	[0..6]	[596..541]
gi\|70725707, gi\|... - gi\|70725707\|ref\|YP_252621.1\| hypothetical protein SH0706 [Staphylococcus haemolyticus JCSC1435], gi\|...	241.0	[0..3]	[590..117]
gi\|49648930 - gi\|49648930\|emb\|CAG81254.1\| YALI0D20196p [Yarrowia lipolytica] gi\|50551177, gi\|... - gi\|50551177\|ref\|XP_503062.1\| YALI0D20196p [Yarrowia lipolytica], gi\|49648930\|emb\|CAG81254.1\| unnamed...	240.0	[0..4]	[594..5]
gi\|116200341, gi... - gi\|88179605\|gb\|EAQ87073.1\| hypothetical protein CHGG_08326 [Chaetomium globosum CBS 148.51], gi\|1162...	237.0	[0..2]	[577..85]
gi\|115396520, gi... - gi\|115396520\|ref\|XP_001213899.1\| predicted protein [Aspergillus terreus NIH2624], gi\|114193468\|gb\|EA...	228.0	[0..22]	[595..419]
gi\|32406262, gi\|... - gi\|32406262\|ref\|XP_323744.1\| hypothetical protein [Neurospora crassa], gi\|28918560\|gb\|EAA28232.1\| hy... gi\|85085267 - gi\|85085267\|ref\|XP_957468.1\| hypothetical protein [Neurospora crassa OR74A]	226.0	[0..15]	[597..19]
gi\|40882232 - gi\|40882232\|emb\|CAF06057.1\| probable aflatoxin efflux pump AFLT [Neurospora crassa]	222.0	[0..15]	[597..19]

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Predicted Domain #1

Region A:
Residues: [1-474]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTENYGSMEH RKKSFRNNEN LEQQFHPLRE ELDNAGPIND RTSELSLEGV SKAEAIASTW  60
   61 SKRSIIVAYL GLYLLSFASS LEQQTTYSLQ RYATSNFSAH SNLATINLVG NILLAVVRAP 120
  121 MVKAADVFGR SESLSLALGM TVLGYLSLAF SRNIQMFTVA YILYICGQTG LGLLSQLIIA 180
  181 DTSSLLNRGI LSAIPELPYL ATVWIGPVLA QAFHPEKNYG WRLGYGIWAF ILPTVSLPLL 240
  241 ASLFLNQRKA KAAGLYREHH NLINHSTPEK LRLFYLFWQE LDGLGIVLFV SGFTLLLLPF 300
  301 SHSSQVVSPD STILTLFTIT LSIALLVTLC FYDVKYARYP VFALKSLKDR TILGSCVLIF 360
  361 TYFMSYYIFS NFLTSFLQVS YGLSIDMSSL TLNVFVFSMT TTAILSGFLM KRFGRFKMLL 420
  421 MISVPMYVLG ILGIILFGIN DNHYTRPLVL VLILAGMGGG LLTLSAQIAV QSVS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.39794
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
substrate-specific transmembrane transporter activity	5.46247398538901	bayes_pls_golite062009
ion transmembrane transporter activity	4.58978526526921	bayes_pls_golite062009
cation transmembrane transporter activity	4.31967711223954	bayes_pls_golite062009
transporter activity	4.09176719149278	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
binding	1.26757615356623	bayes_pls_golite062009
anion transmembrane transporter activity	1.24023641504332	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [475-597]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHAKLGMNLT LYLTFSSVGG AFGSAIAGGV WSKRLSSRLL HDLKDHLPVP EIESIFRDLR  60
   61 TALSYPQGTQ IRNIINVAYT ATEKDLFHIS LVASLFMFAG LVIIRDVPLS TENHDTAVET 120
  121 PSE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: