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Protein Overview: gcn5

General Information:
Name(s) found: gcn5 / SPAC1952.05 [Sanger Pombe]
Description(s) found:
Found 23 descriptions.
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  • histone acetyltransferase Gcn5 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 454 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [IC]
    SAGA complex [ISSLink to PubMed article]
    Biological Process: histone H3 acetylation [IDALink to PubMed article]
    chromatin remodeling [IGILink to PubMed article]
    reciprocal meiotic recombination [IMPLink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [ISSLink to PubMed article]
    Molecular Function: H3 histone acetyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNSLNDQTR PPDSSVVDST SSNFPNASND SVHDKPVKQD EQSNPNVREA IANSDGQESL  60
   61 AVKENKDTES SSSHFVPNGV SNSKKRKLVA TDLDVDFDIS SVRVTEKPSV LEEKSGVIQF 120
  121 RVVSNDDTAD SMIMLTGLKN IFMKQLPKMP KEYITRLIYD RNHLSMTIVK DNLHVVGGIT 180
  181 YRPFEQRGFA EIVFCAIASN EQVRGYGSHL MNHLKDYVRG TTTIQHFLTY ADNYAIGYFK 240
  241 KQGFTKEITL DKSIWVGYIK DYEGGTLMQC TMIPKIKYLE ANLILAIQKA AVVSKINRIT 300
  301 RSNVVYPGLD VFKDGPAHIE PSQVPGLMEV GWCKEMEELS KKPRPKPFFA VLEMLFTEMQ 360
  361 NHPSSWPFMQ PVSKEDVPDY YEVIEHPMDL STMEFRLRNN QYESVEEFIR DAKYIFDNCR 420
  421 SYNDSNTTYY KNADRLEKFF QKKLRETEYS HLAD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] deduced N/A No confident structure predictions are available.
    2 View Details [104..204] PSI-BLAST 66.045757 Catalytic domain of GCN5 histone acetyltransferase
    3 View Details [205..280] FFAS03 3.78 Catalytic domain of GCN5 histone acetyltransferase
    4 View Details [281..454] PSI-BLAST 34.0 GCN5

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • histone acetyltransferase activity
    		•  9.77190406882468 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  9.77190406882468 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  9.73964376866211 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  9.60609829597779 bayes_pls_golite062009
  • acetyltransferase activity
    		•  8.97813893741415 bayes_pls_golite062009
  • acyltransferase activity
    		•  8.29975737946923 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  8.2593462862836 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  8.04883596198777 bayes_pls_golite062009
    		• 6.86025120243744 bayes_pls_golite062009
  • H3 histone acetyltransferase activity
    		•  5.83499424263076 bayes_pls_golite062009
    		• 3.52813815101294 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  3.06288276492113 bayes_pls_golite062009
  • transferase activity
    		•  2.55875279009494 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.26346740872821 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.14720849412601 bayes_pls_golite062009
  • catalytic activity
    		•  1.823104805379 bayes_pls_golite062009
  • binding
    		•  1.30356860355657 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.05620338082006 bayes_pls_golite062009
  • transcription factor binding
    		•  0.999468823887739 bayes_pls_golite062009
  • transcription activator activity
    		•  0.800725992277502 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.60912193595326 bayes_pls_golite062009
  • histone binding
    		•  0.511669465942587 bayes_pls_golite062009
  • glycylpeptide N-tetradecanoyltransferase activity
    		•  0.333301232703043 bayes_pls_golite062009
  • myristoyltransferase activity
    		•  0.333301232703043 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.207688916644661 bayes_pls_golite062009
  • protein binding
    		•  0.116359302536336 bayes_pls_golite062009
    4
    Term Confidence Notes
  • histone acetyltransferase activity
    		•  9.91927576220387 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  9.91927576220387 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  7.57346092874507 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  7.12398761720889 bayes_pls_golite062009
  • acetyltransferase activity
    		•  6.51488433263281 bayes_pls_golite062009
  • acyltransferase activity
    		•  5.44980261163837 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  5.38368530556466 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  5.26899007107713 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  5.06705016462047 bayes_pls_golite062009
    		• 4.94702795409425 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.81944587687526 bayes_pls_golite062009
  • DNA binding
    		•  3.34863990009219 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.25178464591722 bayes_pls_golite062009
  • binding
    		•  3.24233563871512 bayes_pls_golite062009
  • histone binding
    		•  2.93206976627622 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.58609800997327 bayes_pls_golite062009
  • transcription coactivator activity
    		•  2.37993162280856 bayes_pls_golite062009
  • transcription factor binding
    		•  2.33866683789609 bayes_pls_golite062009
  • transcription activator activity
    		•  1.99519727421308 bayes_pls_golite062009
  • MyoD binding
    		•  1.89625280750577 bayes_pls_golite062009
  • MRF binding
    		•  1.89625280750577 bayes_pls_golite062009
  • chromatin binding
    		•  1.85568770971367 bayes_pls_golite062009
  • protein binding
    		•  1.82955314054861 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.82747962293997 bayes_pls_golite062009
  • protein kinase activity
    		•  1.63512839295568 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.60584871002187 bayes_pls_golite062009
  • transcription factor activity
    		•  1.30026489619787 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.28824771134976 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  1.15145628425168 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.08961199627679 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.07760436003896 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  0.96034823197127 bayes_pls_golite062009
  • kinase activity
    		•  0.890638513095454 bayes_pls_golite062009
  • peroxisome proliferator activated receptor binding
    		•  0.547697825358481 bayes_pls_golite062009
  • structural molecule activity
    		•  0.398844600914114 bayes_pls_golite062009
  • transferase activity
    		•  0.321534577277088 bayes_pls_golite062009
  • RNA polymerase binding
    		•  0.29341314806541 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.0167144924052265 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle