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Protein Overview: SPBC2A9.04c

General Information:
Name(s) found: SPBC2A9.04c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • sir antagonist ortholog [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 741 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: chromatin silencing [ISSLink to PubMed article]
    chromatin organization [ISSLink to PubMed article]
    ubiquitin-dependent protein catabolic process [ISSLink to PubMed article]
    protein ubiquitination [ICLink to PubMed article]
    Molecular Function: ubiquitin-protein ligase activity [ISSLink to PubMed article]
    zinc ion binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSNTNENNS HASSNERQSS EGHDDYLNRN PNSEATEGEE GTHPTTGTQP VAFSIGTMFI  60
   61 ITPQANFEGG ENDPFANPFQ PPVKRAVKEA WDSFEPLSND QLMDLTCPIC YDDMNENDEK 120
  121 QATKMPCGHI FGKNCLQKWL ENHCTCPLCR KEVPHETVGS AHPPILFIIP HSHTLRGNQG 180
  181 NTAVSQENAS NGVHSDFHPS EELNNANTDG RTGVDEPARQ LHRIAFNRIR FILAPNRSAT 240
  241 NTPVENTHPE NPDSNTSTPT TRSEPLAGEG ASIDAENASS RQETTPSDSR PSTLTSLFNA 300
  301 FFSSMPDRPS SNEPMTSNLT SNSGSMTNST STDLPTSNLP SQNAPARPVE PSPSIQPPNL 360
  361 LNLPTASPES TSWLPGSQTN IPANTNRSER PFTQLMTFHG LPSLADLPAV LESMFRPSGN 420
  421 NNLLNLNGIF HPDHNAQTEN GQTLPENTDD TNSNATSAVP NLQNLNQQNA VTMGTNTPNN 480
  481 GSSPAVHPVI HIYLSRPPLQ PAVSEQETPS EAVSREGTRS TDATMEDSSR PPSNGSFQGP 540
  541 GITHLSEMGQ RILQRFQEEM ENRMNQTRSE SSTPAQQSAA GSSINVDTAG RQPSDEINIP 600
  601 GEYENSSEVA GSRNQTPTHS SIAVDTLSNV AVDQPAISTP SDVVGSDAGD TSKVSSGTST 660
  661 PRMAAPIARR SNRHHPYSRP SSTRPQCQLE DQGICDPNDR FVHFECGHSV HERCQQSTSN 720
  721 SENQMDEEIG ECPKCRNEEH K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..160] FFAS03 3.17 Crystal Structure of The Cand1-Cul1-Roc1 Complex
    2 View Details [161..306] deduced N/A No confident structure predictions are available.
    3 View Details [307..477] MSA 2.194989 View MSA. No confident structure predictions are available.
    4 View Details [478..741] MSA 3.200995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  5.25982737281228 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  5.16068345159314 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.24782814163304 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.79292110382407 bayes_pls_golite062009
  • binding
    		•  2.70912934275371 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.69310847474187 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.31493818053907 bayes_pls_golite062009
  • DNA binding
    		•  2.0126776192216 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91556680192956 bayes_pls_golite062009
  • protein binding
    		•  1.48593945455888 bayes_pls_golite062009
  • transcription factor activity
    		•  1.23220438818624 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  1.02238152139385 bayes_pls_golite062009
  • transcription factor binding
    		•  0.987482369490121 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  0.821040441472875 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.356312424125648 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.308921486763847 bayes_pls_golite062009
  • ligase activity
    		•  0.227034354896905 bayes_pls_golite062009
  • hydrolase activity
    		•  0.185228576891116 bayes_pls_golite062009
  • catalytic activity
    		•  0.168711389690753 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.137379573046724 bayes_pls_golite062009
  • transcription activator activity
    		•  0.111490592727037 bayes_pls_golite062009
  • peptidase activity
    		•  0.107857202210184 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  0.0136579100966835 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle