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View Structure Prediction Details

Protein: SPBC2A9.04c
Organism: Schizosaccharomyces pombe
Length: 741 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC2A9.04c.

Description E-value Query
Range
Subject
Range
gi|37930527, gi|... - gi|37930527|gb|AAP74661.1| elicitor-like transglutaminase M81 [Phytophthora infestans], gi|23505399|...
263.0 [0..5] [728..684]
gi|39592304, gi|... - gi|39592304|emb|CAE75525.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae], gi|187020927|em...
gi|157762282 - gi|157762282|ref|XP_001673483.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae AF16]
259.0 [0..2] [732..1290]
gi|33310026 - gi|33310026|gb|AAQ03243.1|AF414112_1 putative cell wall protein FLO11p [Candida albicans]
gi|68482880, gi|... - gi|68482880|ref|XP_714666.1| putative cell wall adhesin [Candida albicans SC5314], gi|46436253|gb|EA...
255.0 [0..3] [739..213]
SLAP1_CLOTH - Cell surface glycoprotein 1 OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 ...
243.0 [0..37] [683..1368]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
227.0 [0..27] [705..761]
gi|15828996 - gi|15828996|ref|NP_326356.1| lipoprotein VSAC (fragment) [Mycoplasma pulmonis UAB CTIP]
gi|14089939, gi|... - pir||E90577 lipoprotein vsaC [imported] - Mycoplasma pulmonis (strain UAB CTIP) (fragment), gi|14089...
216.0 [0..21] [737..107]
Muc12Ea-PA - The gene Mucin 12Ea is referred to in FlyBase by the symbol Dmel\Muc12Ea (CG32602, FBgn0052602). It ...
212.0 [0..5] [731..2327]
gi|45190584, gi|... - gi|45190584|ref|NP_984838.1| AEL023Cp [Ashbya gossypii ATCC 10895], gi|44983526|gb|AAS52662.1| AEL02...
gi|44983526 - gi|44983526|gb|AAS52662.1| AEL023Cp [Ashbya gossypii ATCC 10895]
206.0 [0..16] [724..264]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSNTNENNS HASSNERQSS EGHDDYLNRN PNSEATEGEE GTHPTTGTQP VAFSIGTMFI  60
   61 ITPQANFEGG ENDPFANPFQ PPVKRAVKEA WDSFEPLSND QLMDLTCPIC YDDMNENDEK 120
  121 QATKMPCGHI FGKNCLQKWL ENHCTCPLCR KEVPHETVGS 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.17
Match: 1u6gB
Description: Crystal Structure of The Cand1-Cul1-Roc1 Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.25982737281228 bayes_pls_golite062009
small conjugating protein ligase activity 5.16068345159314 bayes_pls_golite062009
acid-amino acid ligase activity 4.24782814163304 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 2.79292110382407 bayes_pls_golite062009
binding 2.70912934275371 bayes_pls_golite062009
transcription regulator activity 2.69310847474187 bayes_pls_golite062009
nucleic acid binding 2.31493818053907 bayes_pls_golite062009
DNA binding 2.0126776192216 bayes_pls_golite062009
transcription repressor activity 1.91556680192956 bayes_pls_golite062009
protein binding 1.48593945455888 bayes_pls_golite062009
transcription factor activity 1.23220438818624 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.02238152139385 bayes_pls_golite062009
transcription factor binding 0.987482369490121 bayes_pls_golite062009
ubiquitin-specific protease activity 0.821040441472875 bayes_pls_golite062009
cysteine-type peptidase activity 0.356312424125648 bayes_pls_golite062009
transcription corepressor activity 0.308921486763847 bayes_pls_golite062009
ligase activity 0.227034354896905 bayes_pls_golite062009
hydrolase activity 0.185228576891116 bayes_pls_golite062009
catalytic activity 0.168711389690753 bayes_pls_golite062009
transcription cofactor activity 0.137379573046724 bayes_pls_golite062009
transcription activator activity 0.111490592727037 bayes_pls_golite062009
peptidase activity 0.107857202210184 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.0136579100966835 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [161-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHPPILFIIP HSHTLRGNQG NTAVSQENAS NGVHSDFHPS EELNNANTDG RTGVDEPARQ  60
   61 LHRIAFNRIR FILAPNRSAT NTPVENTHPE NPDSNTSTPT TRSEPLAGEG ASIDAENASS 120
  121 RQETTPSDSR PSTLTSLFNA FFSSMP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [307-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRPSSNEPMT SNLTSNSGSM TNSTSTDLPT SNLPSQNAPA RPVEPSPSIQ PPNLLNLPTA  60
   61 SPESTSWLPG SQTNIPANTN RSERPFTQLM TFHGLPSLAD LPAVLESMFR PSGNNNLLNL 120
  121 NGIFHPDHNA QTENGQTLPE NTDDTNSNAT SAVPNLQNLN QQNAVTMGTN T

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [478-741]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNNGSSPAVH PVIHIYLSRP PLQPAVSEQE TPSEAVSREG TRSTDATMED SSRPPSNGSF  60
   61 QGPGITHLSE MGQRILQRFQ EEMENRMNQT RSESSTPAQQ SAAGSSINVD TAGRQPSDEI 120
  121 NIPGEYENSS EVAGSRNQTP THSSIAVDTL SNVAVDQPAI STPSDVVGSD AGDTSKVSSG 180
  181 TSTPRMAAPI ARRSNRHHPY SRPSSTRPQC QLEDQGICDP NDRFVHFECG HSVHERCQQS 240
  241 TSNSENQMDE EIGECPKCRN EEHK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle