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Protein Overview: sap61

General Information:
Name(s) found: sap61 / SPBC36.09 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • U2 snRNP-associated protein sap61 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 492 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    spliceosomal complex [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    U2 snRNP [ISSLink to PubMed article]
    Biological Process: nuclear mRNA splicing, via spliceosome [ISSLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    RNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSESVLETER YAHEELERLQ QAIVDRQVAN PKAPRERLRL EHQSAQFLNQ FRETSKKLLV  60
   61 SHESSDRLKD QEVARINADD DLTEFYKSLG EIQEFHKKYP DHKVEDLSQL YSIKPSQPGI 120
  121 DEIDTLFRGE EMYGRFMDLN ECYEEYINLS NVQHISYLEY LKNLEDFDQI PKPEKNQTYI 180
  181 NYITHLYEYL VSFYRRTHPL SNLDKIIAVF DTEFDAAWEA GLPGWYSHNA EAEKDGKDST 240
  241 EAFYCEVCQK FFGKITVFEA HKKSKAHNKA VKRMQSSSPS TTSNTNEKQK GPKAIARIEF 300
  301 LIKKLTSLLD DVRKDTRENV VRRQTLTAAE RLAEVEAAER EAFEQSTPSV SVEGNQDEES 360
  361 DQDDEEKIYN PLKLPLGWDG KPIPFWLWKL HGLGKEFPCE ICGNYVYMGR KAFDKHFTEQ 420
  421 RHIYGLKCLG ISPSPLFNQI TSIDEALQLW QKYKVDSKKR ETTMASLNEM EDDEGNVMSE 480
  481 KVYNDLKAQG LL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..196] MSA 1.037955 View MSA. No confident structure predictions are available.
    2 View Details [197..349] FFAS03 2.15 Solution Structure of a Human C2H2-type Zinc Finger Protein
    3 View Details [350..492] MSA 2.042961 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  3.37529385176635 bayes_pls_golite062009
  • DNA binding
    		•  3.3049326844117 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.24981360535232 bayes_pls_golite062009
  • snRNA binding
    		•  3.16782731106334 bayes_pls_golite062009
  • RNA binding
    		•  3.11293528368816 bayes_pls_golite062009
  • binding
    		•  2.99742524370422 bayes_pls_golite062009
  • U1 snRNA binding
    		•  2.86343975521155 bayes_pls_golite062009
  • transcription factor activity
    		•  2.44389510173662 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.57041104288348 bayes_pls_golite062009
  • mRNA binding
    		•  1.28525296322454 bayes_pls_golite062009
  • transcription activator activity
    		•  1.20323819132961 bayes_pls_golite062009
  • protein binding
    		•  0.952480850696098 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.732558534458316 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.686318575498149 bayes_pls_golite062009
  • chromatin binding
    		•  0.626365497850853 bayes_pls_golite062009
  • transcription factor binding
    		•  0.515821187939278 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.380243728411498 bayes_pls_golite062009
  • catalytic activity
    		•  0.263007611601737 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.200483461579207 bayes_pls_golite062009
  • tubulin binding
    		•  0.151955152284472 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.113925660147477 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0855506955761403 bayes_pls_golite062009
  • microtubule binding
    		•  0.05082413668213 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle