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Protein Overview: png2

General Information:
Name(s) found: png2 / SPBC1709.11c [Sanger Pombe]
Description(s) found:
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  • pir||T39639 conserved protein-PHD-finger family - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74626909|sp|O74736.1|ING2_SCHPO RecName: Full=Chromatin modification-related protein png2; AltName: Full=ING1 homolog 2 [NCBI NR]
  • gi|3738149|emb|CAA21250.1| ING family homolog Png2 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112236|ref|NP_595444.1| ING family homolog Png2 [Schizosaccharomyces pombe] [NCBI NR]
  • ING family homolog Png2 [Sanger Pombe]
  • Chromatin modification-related protein png2 OS=Schizosaccharomyces pombe GN=png2 PE=1 SV=1 [Swiss-Prot]
  • ZINC FINGER PROTEIN; ZF-PHD FINGER; SIMILAR TO HUMAN CANDIDATE TUMOR SUPPRESSOR P33(ING1) IN THEIR C- TERMINAL REGIONS; POSSIBLY INVOLVED IN CHROMATIN MEDIATED TRANSCRIPTIONAL REGULATION; ASSOCIATED WITH HISTONE ACETYLTRANSFERASE ACTIVITIES; SIMILAR TO [pompepVF.fasta]
  • CONSERVED PROTEIN; PHD-FINGER FAMILY PROTEIN; SHARES SIGNIFICANT SEQUENCE IDENTITY WITH THE HUMAN CANDIDATE TUMOR SUPPRESSOR P33(ING1) IN THEIR C-TERMINAL REGIONS; HOMOLOGOUS REGIONS CONTAIN PHD FINGER DOMAINS WHICH HAVE BEEN IMPLICATED IN CHROMATIN-ME [pompepV13]
  • Conserved protein-PHD-finger family [pompep4896]
  • |png2||zinc finger protein [pompepnew.fasta]
  • Png2 protein (Spbc1709.11c protein) [4896.FASTAC]
  • |png2||zinc finger protein|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • conserved protein-PHD-finger family [Schizosaccharomyces pombe]gi|3738149|emb|CAA21250.1| SPBC1709.11c [Schizosaccharomyces pombe]gi|7490391|pir||T39639 conserved protein-PHD-finger family - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • (O74736) Conserved protein-PHD-finger family [pompep4896_normal_reversed]
  • |png2||ING family homolog Png2|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPBC1709.11c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC1709.11c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Chromatin modification-related protein png2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=png2 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 305 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Rpd3L-Expanded complex [IDALink to PubMed article]
    Rpd3L complex [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Rpd3S complex [IDALink to PubMed article]
    histone acetyltransferase complex [ISSLink to PubMed article]
    Biological Process: chromatin modification [ISSLink to PubMed article]
    chromatin remodeling [NAS]
    histone acetylation [ISSLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    methylated histone residue binding [ISSLink to PubMed article]
    small conjugating protein ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTSGIEIFA ALNDFTDAIV SVPESVCGKF TSLKEIDAQV RDIRQNVIQE IGVVLKNEKN  60
   61 DELSGEERCE RLQKTLKEIL PYSDSKICLA TDAMNNIKSC IDRLDAGFEY VELEIPQQLR 120
  121 LGYPDDRALM NYHSTVTPQT SERRRETRRH QNNQHSQQYS SQERSSSYNN FEDASSPQSS 180
  181 YHTPTKRRKN AVPRKSSSPP LSSTKHAPQS TERRPVRRSE SRLKQTNGEP LVKHDTLDSS 240
  241 DISREGEQLY CYCQQVSYGQ MIGCDNENCK REWFHLPCVG LVEPPKGIWY CKECEELAKS 300
  301 SESRQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..209] MSA 6.35699 View MSA. No confident structure predictions are available.
    2 View Details [210..305] PSI-BLAST 18.0 Solution structure of PHD domain in ING1-like protein BAC25009

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • protein deacetylase activity
    		•  7.50578521120904 bayes_pls_golite062009
  • histone deacetylase activity
    		•  7.35162059871663 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  7.10262960897544 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  7.10262960897544 bayes_pls_golite062009
  • deacetylase activity
    		•  6.55925777139018 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  5.24378850198774 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  5.0952093808777 bayes_pls_golite062009
    		• 4.93977737347339 bayes_pls_golite062009
    		• 4.75659254650148 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  4.73470737654883 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  4.39452339322141 bayes_pls_golite062009
  • acetyltransferase activity
    		•  4.29938591960121 bayes_pls_golite062009
  • methylated histone residue binding
    		•  4.19057851212315 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.59302841227183 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.54892905221507 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.34035867339622 bayes_pls_golite062009
  • histone binding
    		•  3.01402804224903 bayes_pls_golite062009
  • binding
    		•  2.78627791259335 bayes_pls_golite062009
  • nucleosome binding
    		•  1.69494047037058 bayes_pls_golite062009
  • protein binding
    		•  1.6308789519356 bayes_pls_golite062009
  • chromatin binding
    		•  1.0360039180364 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.01735624308761 bayes_pls_golite062009
  • DNA binding
    		•  0.896491359501813 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.723245820583374 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.655033722565177 bayes_pls_golite062009
  • kinase activity
    		•  0.596989785523293 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  0.476506467104495 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.465950484314184 bayes_pls_golite062009
  • protein kinase activity
    		•  0.405766438875014 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.327424740985033 bayes_pls_golite062009
  • transferase activity
    		•  0.245705939593188 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K4 specific)
    		•  0.0490968711985191 bayes_pls_golite062009
  • histone acetyl-lysine binding
    		•  0.0410393640547611 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle