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Protein Overview: vps36

General Information:
Name(s) found: vps36 / SPBC3B9.09 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • RBZ zinc finger protein Vps36 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 467 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    ESCRT II complex [ISSLink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    Biological Process: protein retention in Golgi apparatus [ISSLink to PubMed article]
    protein targeting to vacuole during ubiquitin-dependent protein catabolic process via the MVB pathway [IMPLink to PubMed article]
    late endosome to vacuole transport [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFYLETTPS NLPVLDPSEE ILLVQDQVGL YFGDEKSFRH NNGTLYLTKK HIFYVDSVDP  60
   61 KKNSLKIKIS DIRDVQHTSR YFRSSPKIRL SLRHVEKSWA CKICTFINVG DPINPCRNCG 120
  121 VANRFTIIKP KSDARFSQGL CTACTFQNYP DLNTCEICGN QLKNVDRNQL IQLSFRGSGS 180
  181 SKFYEAIKSE TDEIEKQRYS NKYDTKVLRK AILEKSLRMG GIHDLEQSHE MQLAKNGRTL 240
  241 VHAFQDLDAF FSLAKDTMSL ADQFAEKMDG LTGTQQSDKV QQLLNKSNQL GVLRGNHLDN 300
  301 VPVSANSRLY DIELCKSISE VLRTRLKADT DTVTMTQAWA IYNRSRKANL IPPTRFVKAC 360
  361 ELIDSMEVGI TTSKMNSGLI LFQLKTSNHS GKLLSAILEV MNPSTTALKC AMRLHWSIGV 420
  421 TLERLYQAEM DGYIVRDVYE ESGSSLLYWK NEFDELSEEL TKWFDES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..467] PSI-BLAST 117.0 ESCRT-II

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  4.95502209146398 bayes_pls_golite062009
  • DNA binding
    		•  4.49877554292304 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.4138116788102 bayes_pls_golite062009
  • transcription factor activity
    		•  3.78905634607011 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.35896772348591 bayes_pls_golite062009
  • binding
    		•  3.09940998297931 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.10135825467854 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.97423148823534 bayes_pls_golite062009
  • transcription activator activity
    		•  1.86787909680028 bayes_pls_golite062009
  • protein binding
    		•  0.753698599635855 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.574575108509588 bayes_pls_golite062009
  • signal transducer activity
    		•  0.574575108509588 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.51900654743421 bayes_pls_golite062009
  • transcription factor binding
    		•  0.35726633913804 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.18158516638045 bayes_pls_golite062009
  • hydrolase activity
    		•  0.140191206949582 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.136726704233672 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.118016217031359 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0384502189988831 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle