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Protein Overview: rmt3

General Information:
Name(s) found: rmt3 / SPBC8D2.10c [Sanger Pombe]
Description(s) found:
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  • gi|74626597|sp|O13648.3|ANM3_SCHPO RecName: Full=Ribosomal protein arginine N-methytransferase rmt3 [NCBI NR]
  • gi|6468730|emb|CAA17825.2| type I ribosomal protein arginine N-methyltransferase Rmt3 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112364|ref|NP_595572.1| type I ribosomal protein arginine N-methytransferase Rmt3 [Schizosaccharomyces pombe] [NCBI NR]
  • type I ribosomal protein arginine N-methytransferase Rmt3 [Sanger Pombe]
  • Ribosomal protein arginine N-methytransferase rmt3 OS=Schizosaccharomyces pombe GN=rmt3 PE=1 SV=3 [Swiss-Prot]
  • PUTATIVE ARGININE N-METHYLTRANSFERASE: O13648; [pompepVF.fasta]
  • Arginine N-methyltransferase [pompep4896]
  • |||zinc finger protein (inferred from context) [pompepnew.fasta]
  • Zinc finger protein (Inferred from context); zf-C2H2 type; arginine N-methyltransferase (Predicted); no apparent S. cerevisiae ortholog (Has homologs) (EC 2.1.1.-) [4896.FASTAC]
  • |||zinc finger protein (inferred from context)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • zinc finger protein (inferred from context); zf-C2H2 type; arginine N-methyltransferase (predicted); no apparent S. cerevisiae ortholog (has homologs) [Schizosaccharomyces pombe]gi|19112364|ref|NP_595572.1| putative arginine n-methyltransferase [Schizosa [nrdb_11152004_Chlamydomonas]
  • |||zinc finger protein |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O13648) Arginine N-methyltransferase [pompep4896_normal_reversed]
  • |rmt3|rmt3|type I ribosomal protein arginine N-methyltransferase Rmt3|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • arginine N-methyltransferase [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC8D2.10c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Ribosomal protein arginine N-methyltransferase rmt3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rmt3 PE=1 SV=3 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 543 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    cytosolic small ribosomal subunit [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [IPILink to PubMed article]
    [NOT]ribosome biogenesis [IMPLink to PubMed article]
    ribosome assembly [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IPILink to PubMed article]
    ribosome binding [IDALink to PubMed article]
    protein-arginine N-methyltransferase activity [IMPLink to PubMed article]
    methyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVKPMACYF EIWTRKVTTI EDFSLAIANR FKQMGSHSDS EVDWDNEEEV WEDEVHEFCC  60
   61 LFCDSTFTCL KDLWSHCKEA HNFDFYQVKQ QNNLDFYACI KLVNYIRSQV KEGKTPDLDK 120
  121 LSDILRSDEY MISVLPDDSV LFSLGDELDS DFEDDNTLEI EVENPADVSK DAEIKKLKLQ 180
  181 NQLLISQLEE IRKDKMNELT SQTTDQLSVT PKKADNDSYY FESYAGNDIH FLMLNDSVRT 240
  241 EGYRDFVYHN KHIFAGKTVL DVGCGTGILS MFCAKAGAKK VYAVDNSDII QMAISNAFEN 300
  301 GLADQITFIR GKIEDISLPV GKVDIIISEW MGYALTFESM IDSVLVARDR FLAPSGIMAP 360
  361 SETRLVLTAT TNTELLEEPI DFWSDVYGFK MNGMKDASYK GVSVQVVPQT YVNAKPVVFA 420
  421 RFNMHTCKVQ DVSFTSPFSL IIDNEGPLCA FTLWFDTYFT TKRTQPIPEA IDEACGFTTG 480
  481 PQGTPTHWKQ CVLLLRNRPF LQKGTRVEGT ISFSKNKKNN RDLDISVHWN VNGKADSQSY 540
  541 VLN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..144] PSI-BLAST 17.69897 Solution structure of the C2H2 zinc finger domain of the protein arginine N-methyltransferase 3 from Mus musculus
    2 View Details [145..209] PSI-BLAST 19.0 Crystal Structure of PH1915 (APC 5817): A Hypothetical RNA Methyltransferase
    3 View Details [210..543] PSI-BLAST 77.0 Structure of the Predominant Protein Arginine Methyltransferase PRMT1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.27542149084008 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.31369346002275 bayes_pls_golite062009
  • transcription activator activity
    		•  2.19952417915035 bayes_pls_golite062009
  • chromatin binding
    		•  1.53640935908107 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.42975942698743 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.42446448463712 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.34049786451995 bayes_pls_golite062009
  • receptor activity
    		•  1.18834908971961 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  1.1674904189309 bayes_pls_golite062009
  • signal transducer activity
    		•  1.12277938241964 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.12277938241964 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.0497955246512 bayes_pls_golite062009
  • protein binding
    		•  1.00484935878505 bayes_pls_golite062009
  • RNA binding
    		•  0.938541269618281 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • histone binding
    		•  0.687710658383448 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.311339098303136 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • arginine N-methyltransferase activity
    		•  5.52520020727046 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  5.52520020727046 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  5.03267617653315 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  4.4632173842967 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  4.42061797259061 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  4.40911163698179 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  4.39379274790202 bayes_pls_golite062009
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  4.07806017452628 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  3.55785970363721 bayes_pls_golite062009
  • protein-arginine omega-N symmetric methyltransferase activity
    		•  3.42560739702664 bayes_pls_golite062009
  • transferase activity
    		•  2.926540904444 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  2.86617323549909 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  2.43145108778901 bayes_pls_golite062009
  • histone methyltransferase activity (H2A-R3 specific)
    		•  2.26179395735928 bayes_pls_golite062009
  • histone methyltransferase activity (H3-R2 specific)
    		•  2.26179395735928 bayes_pls_golite062009
  • [myelin basic protein]-arginine N-methyltransferase activity
    		•  2.10091845446893 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.0187748912503 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  1.93505048403302 bayes_pls_golite062009
  • DNA binding
    		•  1.86585662505513 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.71901340148111 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.11388181877851 bayes_pls_golite062009
  • signal transducer activity
    		•  1.11388181877851 bayes_pls_golite062009
  • binding
    		•  0.976078016260105 bayes_pls_golite062009
  • histone binding
    		•  0.964746527369069 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  0.817509452491588 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.703178429468566 bayes_pls_golite062009
  • RNA binding
    		•  0.460713129603544 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  0.229189844833659 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  0.152064081957651 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle