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Protein Overview: rfp1

General Information:
Name(s) found: rfp1 / SPAC19A8.10 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • ubiquitin-protein ligase E3 Rfp1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 254 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    SUMO-targeted ubiquitin ligase complex [IPILink to PubMed article]
    Biological Process: DNA repair [IGILink to PubMed article]
    negative regulation of protein sumoylation [IGILink to PubMed article][IMPLink to PubMed article]
    response to DNA damage stimulus [IGILink to PubMed article]
    regulation of ubiquitin-protein ligase activity [IMPLink to PubMed article]
    regulation of mitotic cell cycle [IGILink to PubMed article]
    protein ubiquitination [IMPLink to PubMed article]
    Molecular Function: [NOT]ubiquitin-protein ligase activity [IDALink to PubMed articleLink to PubMed article]
    zinc ion binding [ISSLink to PubMed article]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQFNGSNGID ESSVIDLTRS PSPPVETSIS STNIIDLDAI PDDSFPSSPV LSPRRRRMNR  60
   61 RRNERSRNFP SNHLSYLEDM IYLGPQVSTR RSSSRRDLMG MIARTFPEFS SVNSLSPSLF 120
  121 QLIVNRMRFD AIHPEWTNGS DDEYFSNHFE ESYDDFTSSL ENIKQSYKPP GPPKSGFTRS 180
  181 FNNDTLMVCP RCQEPLGTSK SKEKSALWAT KCGHVYCGSC AKVLKTSKRS QSKCLVNDCG 240
  241 RYLNTKNAMW ELFY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..163] deduced N/A No confident structure predictions are available.
    2 View Details [164..254] FFAS03 2.02 brca1 RING domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  9.85513873918659 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  9.6498820226444 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  8.65014213775678 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  7.41958646938187 bayes_pls_golite062009
  • ligase activity
    		•  3.71574519150582 bayes_pls_golite062009
  • binding
    		•  2.70912934275371 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.9010236336815 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.64351954613384 bayes_pls_golite062009
  • protein binding
    		•  1.48593945455888 bayes_pls_golite062009
  • DNA binding
    		•  1.37350981563815 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  1.35297260222963 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.33893730503955 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  1.02238152139385 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  0.821040441472875 bayes_pls_golite062009
  • transcription factor binding
    		•  0.742650421609881 bayes_pls_golite062009
  • transcription factor activity
    		•  0.68618471403445 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.356312424125648 bayes_pls_golite062009
  • catalytic activity
    		•  0.168711389690753 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  0.0136579100966835 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle