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View Structure Prediction Details

Protein: rfp1
Organism: Schizosaccharomyces pombe
Length: 254 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rfp1.

Description E-value Query
Range
Subject
Range
gi|32410143, gi|... - gi|32410143|ref|XP_325552.1| predicted protein [Neurospora crassa], gi|28924709|gb|EAA33823.1| predi...
gi|85109729 - gi|85109729|ref|XP_963059.1| hypothetical protein NCU05697 [Neurospora crassa OR74A]
120.0 [0..170] [233..591]
gi|66850940, gi|... - gi|70997099|ref|XP_753304.1| RING finger domain protein [Aspergillus fumigatus Af293], gi|66850940|g...
117.0 [0..156] [253..224]
gi|67541470, gi|... - gi|67541470|ref|XP_664509.1| hypothetical protein AN6905.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
108.0 [0..156] [214..215]
gi|119174814, gi... - gi|90298521|gb|EAS28152.1| predicted protein [Coccidioides immitis RS], gi|119174814|ref|XP_00123973...
102.0 [0..165] [253..277]
gi|111055439, gi... - gi|169625417|ref|XP_001806112.1| hypothetical protein SNOG_15980 [Phaeosphaeria nodorum SN15], gi|11...
99.0 [0..157] [253..352]
gi|42545110, gi|... - gi|46111647|ref|XP_382881.1| hypothetical protein FG02705.1 [Gibberella zeae PH-1], gi|42545110|gb|E...
89.0 [0..156] [228..241]
gi|114192219, gi... - gi|115399494|ref|XP_001215336.1| predicted protein [Aspergillus terreus NIH2624], gi|114192219|gb|EA...
87.0 [0..161] [215..278]
gi|88181298, gi|... - gi|88181298|gb|EAQ88766.1| hypothetical protein CHGG_05385 [Chaetomium globosum CBS 148.51], gi|1161...
75.0 [0..173] [249..188]

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Predicted Domain #1
Region A:
Residues: [1-163]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQFNGSNGID ESSVIDLTRS PSPPVETSIS STNIIDLDAI PDDSFPSSPV LSPRRRRMNR  60
   61 RRNERSRNFP SNHLSYLEDM IYLGPQVSTR RSSSRRDLMG MIARTFPEFS SVNSLSPSLF 120
  121 QLIVNRMRFD AIHPEWTNGS DDEYFSNHFE ESYDDFTSSL ENI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [164-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQSYKPPGPP KSGFTRSFNN DTLMVCPRCQ EPLGTSKSKE KSALWATKCG HVYCGSCAKV  60
   61 LKTSKRSQSK CLVNDCGRYL NTKNAMWELF Y

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.02
Match: 1jm7A
Description: brca1 RING domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 9.85513873918659 bayes_pls_golite062009
small conjugating protein ligase activity 9.6498820226444 bayes_pls_golite062009
acid-amino acid ligase activity 8.65014213775678 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 7.41958646938187 bayes_pls_golite062009
ligase activity 3.71574519150582 bayes_pls_golite062009
binding 2.70912934275371 bayes_pls_golite062009
transcription regulator activity 1.9010236336815 bayes_pls_golite062009
nucleic acid binding 1.64351954613384 bayes_pls_golite062009
protein binding 1.48593945455888 bayes_pls_golite062009
DNA binding 1.37350981563815 bayes_pls_golite062009
NEDD8 ligase activity 1.35297260222963 bayes_pls_golite062009
transcription repressor activity 1.33893730503955 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.02238152139385 bayes_pls_golite062009
ubiquitin-specific protease activity 0.821040441472875 bayes_pls_golite062009
transcription factor binding 0.742650421609881 bayes_pls_golite062009
transcription factor activity 0.68618471403445 bayes_pls_golite062009
cysteine-type peptidase activity 0.356312424125648 bayes_pls_golite062009
catalytic activity 0.168711389690753 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.0136579100966835 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle