YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residues of a small conjugating protein such as ubiquitin or a ubiquitin-like protein, and a substrate lysine residue. This function may be performed alone or in conjunction with an E3, ubiquitin-like protein ligase. Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residues of the small ubiquitin-related modifier NEDD8 and a substrate lysine residue.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: NEDD8 ligase activity
Acc: GO:0019788
Aspect: Molecular Function
Desc: Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residues of the small ubiquitin-related modifier NEDD8 and a substrate lysine residue.
Synonyms:
  • GO:0016976
  • GO:0019945
  • NEDD8 conjugating enzyme activity
  • GO:0042295
  • Hub1 conjugating enzyme activity
  • RUB1 conjugating enzyme activity
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0019788 - NEDD8 ligase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle