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Protein Overview: SPAC16C9.04c

General Information:
Name(s) found: SPAC16C9.04c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • CCR4-Not complex subunit Mot2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 489 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    CCR4-NOT core complex [RCALink to PubMed article]
    CCR4-NOT complex [ISSLink to PubMed article]
    Biological Process: negative regulation of transcription [ICLink to PubMed article]
    mRNA catabolic process [ICLink to PubMed article]
    nuclear-transcribed mRNA poly(A) tail shortening [ISSLink to PubMed article]
    RNA elongation from RNA polymerase II promoter [ISS]
    protein ubiquitination [ISSLink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [ISSLink to PubMed article]
    Molecular Function: ubiquitin-protein ligase activity [ISSLink to PubMed article]
    zinc ion binding [IEA]
    RNA binding [ISSLink to PubMed article]
    transcription repressor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKTQEIYSS EDEDDMCCPL CMEEIDISDK NFKPCQCGYR VCRFCWHHIK EDLNGRCPAC  60
   61 RRLYTEENVQ WRPVTAEEWK MDLHRKNERK KREKERKEVE LSNRKHLANI RVVQKNLAYV 120
  121 NGLSPKVANE ENINVLKGPE YFGQYGKIIK IAINKKAAAN SANGHVGVYI TYQRKEDAAR 180
  181 AIAAIDGSVS DGRHLRASYG TTKYCTSYLR NQQCPNPSCM YLHEPGDEVD SYTKEDLASL 240
  241 QHTRPLSTKP NVVNGATHSP SPSLPFKTPL LPVTKTPLEE ANSSPAAQNQ HITTVDHVHP 300
  301 QVSMTPSLST NNTATSVPAP YSSAASVNVV PGHATTILHH EESSALPPTA AWAKLSPSVL 360
  361 QERLRAAVNQ QPLDALKSSS TQTSIPKIQK LKAAKLPSEE ENTTKWLNKA INDLVSSLSK 420
  421 INFSTEGTEF DKKQIEMIQN LPPLFVFNAR SVIDKEVVPE QEKSAENQPP TSLGINNGNP 480
  481 VMPPPGFQS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..100] PSI-BLAST 11.69897 Not-4 N-terminal RING finger domain
    2 View Details [101..212] PSI-BLAST 5.522879 Solution structure of the RNA recognition motif of CNOT4
    3 View Details [213..274] deduced N/A No confident structure predictions are available.
    4 View Details [275..489] PSI-BLAST 3.522879 Sec24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  5.97121728620188 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  5.78935175140238 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.75377804653841 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  3.82459130917693 bayes_pls_golite062009
  • binding
    		•  2.78710909602478 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.72498741013971 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.32387297115017 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.11206038007886 bayes_pls_golite062009
  • DNA binding
    		•  2.00904221080834 bayes_pls_golite062009
  • protein binding
    		•  1.5975811408548 bayes_pls_golite062009
  • RNA binding
    		•  1.46657863864484 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22579085356684 bayes_pls_golite062009
    		• 1.22378902883043 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  1.2126425713931 bayes_pls_golite062009
  • transcription factor binding
    		•  1.11842175076436 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  1.03469202541773 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.90321253993065 bayes_pls_golite062009
  • ligase activity
    		•  0.63517530468004 bayes_pls_golite062009
  • hydrolase activity
    		•  0.52386813728704 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.50197530717959 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.350170315296021 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  0.265769062717221 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.255669498391574 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.233838999434784 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
  • transcription activator activity
    		•  0.126093965701234 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle