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Protein Overview: trk2

General Information:
Name(s) found: trk2 / SPAC1639.02c [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • potassium ion transporter Trk2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 880 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: potassium ion transport [IGILink to PubMed article]
    cellular potassium ion homeostasis [TASLink to PubMed article]
    regulation of membrane potential [IMPLink to PubMed article]
    transmembrane transport [IEA]
    response to drug [IMPLink to PubMed article]
    response to cation stress [NASLink to PubMed article]
    Molecular Function: potassium ion transmembrane transporter activity [TASLink to PubMed article]
    potassium ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLSGFSTNG SGSLNTIVCE KLLFKPNFVQ DSFIIGMTIL CSVILYGSGN LRYIDALLLA  60
   61 SGSCTQTGLQ PVDLTQISIY QQLTILLFGV LSTPITVNLG LTLFKLYFYN KRYDMVITNN 120
  121 KLRMTYTYHT VRRRDTPEPS KVGNRKIRVL LDQGNQMHRP VAPETKAEEA EHQENEKHHR 180
  181 HHFRLRKFAN AIDRPSFFRG NTMPALPSYA GVRNSQENED RTEALSPALG KRRMASIDNG 240
  241 SLSVVQNNAR NNPVDFYIPS SFEESSFQTI PEDFEPQVHD HENQTQLNHH LDNNSSISSH 300
  301 NPSLETANDG NQETVSSSNS NYSTTRVDND PHVASYSPQN SNFDHQAAAT TNDAHQNVVR 360
  361 GSAITIAPTP VPRHNRRPIY FADDTNGAEQ EKGAHRLDGR GRKRGKSFAV TPTLHRNERS 420
  421 MSVLPFQLAK SFTSALPRRL TFNRTHTKAS TMSLPYLSYN ATVGRNSAFY ALTPVEREEL 480
  481 AGIEYESLRI LTVILVVYFL FWHILGLVAF LIFIYTAKTS GRVVTDGGIN RGWWAAFTSS 540
  541 SLFDNLGYSL NSDSLNSFQK AIFPQVLGTI LIFLGNTFFP IMLRFIIWIM IRTTRFSPNF 600
  601 QQALYFLFEH PRRSFTLLFP SKTTWVLFLN LTLLNFASFF FFMVLDLGNS YVDKIPVGYR 660
  661 IMNAIFQNAA TRSAGFTVVD LSQIAPAVMV TYMFMMYISA YPIAMSIRQT NVYEERSLGI 720
  721 YAADTENDDD NNINNNNNDN NTPKRKNFLM DHIQRQLSHD LWYLFLGYFI ITIVEGRRLE 780
  781 SEAEPQFTLF AILFEVISGY GTVGLSLGYK NDPSLTAQFR KISKLVMVAL QIRGRHRGLP 840
  841 SALDRAVLMP SDKNFDREEE DYMRRHGKKN TNRADPVPSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..122] FFAS03 1.4 Potassium channel protein
    2 View Details [123..451] FFAS03 1.68 30S subunit
    3 View Details [452..880] FFAS03 1.08 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • potassium channel activity
    		•  6.97421456325005 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  6.93926669126255 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  6.85197806762042 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  6.68953517879833 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  6.66667969342152 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  5.60647618241473 bayes_pls_golite062009
  • cation channel activity
    		•  5.09551684793166 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.88789838906314 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.80939024913503 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  4.64079808042939 bayes_pls_golite062009
  • ion channel activity
    		•  4.50553553033114 bayes_pls_golite062009
  • gated channel activity
    		•  4.47618233399604 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.43208330555032 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  4.39833449623615 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  4.38139555510307 bayes_pls_golite062009
  • channel activity
    		•  4.38139555510307 bayes_pls_golite062009
  • transporter activity
    		•  2.77619896060397 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.65613366364107 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  2.63030973607925 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  2.63030973607925 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.60593795082679 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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