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Protein Overview: rhp23

General Information:
Name(s) found: rhp23 / SPBC2D10.12 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • Rad23 homolog Rhp23 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 368 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    nucleus [IDALink to PubMed articleLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: proteasomal ubiquitin-dependent protein catabolic process [TASLink to PubMed article]
    negative regulation of protein catabolic process [IMPLink to PubMed article]
    nucleotide-excision repair [IMPLink to PubMed article]
    ER-associated protein catabolic process [ISSLink to PubMed article]
    regulation of mitotic cell cycle [TASLink to PubMed article]
    protein ubiquitination [IMPLink to PubMed article]
    Molecular Function: ubiquitin binding [IDALink to PubMed article]
    polyubiquitin binding [TASLink to PubMed article]
    damaged DNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLTFKNLQQ QKFVISDVSA DTKISELKEK IQTQQNYEVE RQKLIYSGRI LADDKTVGEY  60
   61 NIKEQDFIVC MVSRPKTSTS TPKSAASPAP NPPASVPEKK VEAPSSTVAE STSTTQTVAA 120
  121 AAPSNPDTTA TSEAPIDANT LAVGAQRNVA VENMVEMGYE RSEVERAMRA AFNNPDRAVE 180
  181 YLLTGIPEDI LNRQREESAA ALAAQQQQSE ALAPTSTGQP ANLFEQAALS ENENQEQPSN 240
  241 TVGDDPLGFL RSIPQFQQLR QIVQQNPQML ETILQQIGQG DPALAQAITQ NPEAFLQLLA 300
  301 EGAEGESALP SGGIQIQITQ EESESIDRLC QLGFDRNIVI QAYLACDKNE ELAANYLFEH 360
  361 GHESEDEP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..368] PSI-BLAST 58.522879 Structure of the DNA repair protein hHR23a

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • damaged DNA binding
    		•  4.47463096529128 bayes_pls_golite062009
  • peptidase activity
    		•  4.11397638448668 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  3.93085931991298 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  3.71144418714309 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  3.30801071565148 bayes_pls_golite062009
  • DNA binding
    		•  2.85587480999529 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.77967439078472 bayes_pls_golite062009
  • hydrolase activity
    		•  2.77871378503369 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  2.72499875710239 bayes_pls_golite062009
  • binding
    		•  2.47268310088535 bayes_pls_golite062009
  • protein tag
    		•  2.08744267430616 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.00465244189638 bayes_pls_golite062009
  • small conjugating protein binding
    		•  1.96968415005987 bayes_pls_golite062009
  • ubiquitin binding
    		•  1.89720476649564 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.42747465816672 bayes_pls_golite062009
  • protein binding
    		•  1.15687168153762 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.80391127659342 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  0.59805675560068 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.570143717979967 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.536856055841234 bayes_pls_golite062009
  • kinase activity
    		•  0.506057697290914 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.410719674374641 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  0.387487703339719 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.366426020658587 bayes_pls_golite062009
  • protein kinase activity
    		•  0.325253662829604 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.249928925871521 bayes_pls_golite062009
  • transferase activity
    		•  0.236208643697075 bayes_pls_golite062009
  • polyubiquitin binding
    		•  0.126322128629172 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle