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Protein Overview: rbx1

General Information:
Name(s) found: rbx1 / SPAC23H4.18c [Sanger Pombe]
Description(s) found:
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  • pir||T38310 pop-interacting protein 1 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|6073753|emb|CAB58559.1| RING-box protein 1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|5853264|gb|AAD54393.1|AF179228_1 pop-interacting protein 1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|26397978|sp|O13959.2|RBX1_SCHPO RecName: Full=RING-box protein pip1; Short=RING-box protein 1; AltName: Full=Pop-interacting protein 1 [NCBI NR]
  • gi|19114300|ref|NP_593388.1| RING-box protein 1 [Schizosaccharomyces pombe] [NCBI NR]
  • RING-box protein 1 [Sanger Pombe]
  • RING-box protein pip1 OS=Schizosaccharomyces pombe GN=pip1 PE=1 SV=2 [Swiss-Prot]
  • PUTATIVE SUBUNIT OF THE SCF-POP UBIQUITIN LIGASE COMPLEX; POP-INTERACTING PROTEIN 1: O13959; [pompepVF.fasta]
  • RING-box protein pip1 (Pop-interacting protein 1) (RING-box protein 1) [pompep4896]
  • |pip1||SCF (skp1-Cullin-1-F-box) ubiquitin ligase complex [pompepnew.fasta]
  • |pip1||SCF ubiquitin ligase complex|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • pop-interacting protein 1. [Schizosaccharomyces pombe]gi|6073753|emb|CAB58559.1| pip1 [Schizosaccharomyces pombe]gi|26397978|sp|O13959|RBX1_SCHPO RING-box protein pip1 (Pop-interacting protein 1) (RING-box protein 1)gi|5853264|gb|AAD54393.1| pop-intera [nrdb_11152004_Chlamydomonas]
  • |pip1||pop-interacting protein 1|Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (O13959) RING-box protein pip1 (Pop-interacting protein 1) (RING-box protein 1) [pompep4896_normal_reversed]
  • |rbx1|pip1|RING-box protein 1|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • pop-interacting protein 1 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • SPAC23H4.18c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC23H4.18c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • RING-box protein pip1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pip1 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 107 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Cul4B-RING ubiquitin ligase complex [TASLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: chromatin modification [IEA]
    protein ubiquitination during ubiquitin-dependent protein catabolic process [ISSLink to PubMed article]
    protein ubiquitination [IDALink to PubMed article]
    Molecular Function: ubiquitin-protein ligase activity [IDALink to PubMed article][ISSLink to PubMed article]
    zinc ion binding [ISSLink to PubMed article]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDEMQIDKK EVEIEQKPPR FEIKKWNAVA LWQWDIVVDN CAICRNHIMD LCIECQANTD  60
   61 SAAAQECTVA WGTCNHAFHF HCISRWLNTR NVCPLDNREW EFQRYGH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..107] PSI-BLAST 22.39794 Crystal Structure of The Cand1-Cul1-Roc1 Complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  10.2497392096259 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  10.0460587929138 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  8.99384576623969 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  7.6988425139962 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  5.61847630780351 bayes_pls_golite062009
  • ligase activity
    		•  3.92677358871643 bayes_pls_golite062009
  • binding
    		•  2.78710909602478 bayes_pls_golite062009
  • protein binding
    		•  1.5975811408548 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  1.2126425713931 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  1.03469202541773 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.943706743211193 bayes_pls_golite062009
  • transcription factor binding
    		•  0.90065892745057 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.708499177773075 bayes_pls_golite062009
  • hydrolase activity
    		•  0.52386813728704 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.50197530717959 bayes_pls_golite062009
  • SUMO polymer binding
    		•  0.417597867824941 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.393708074680332 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.392372133643049 bayes_pls_golite062009
  • DNA binding
    		•  0.365874679056682 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  0.265769062717221 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
  • enzyme binding
    		•  0.104373352314595 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle