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Protein Overview: pof11

General Information:
Name(s) found: pof11 / SPAC29E6.01 [Sanger Pombe]
Description(s) found:
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  • gi|6723888|emb|CAB66464.1| F-box protein Pof11 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19862893|sp|Q09855.2|POF11_SCHPO RecName: Full=F-box/WD repeat-containing protein pof11; AltName: Full=Meiotically up-regulated gene 156 protein [NCBI NR]
  • gi|19115471|ref|NP_594559.1| F-box protein Pof11 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|14090330|dbj|BAB55543.1| F-box protein Pof11 [Schizosaccharomyces pombe] [NCBI NR]
  • pir||T50211 WD-repeat protein [imported] - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • F-box protein Pof11 [Sanger Pombe]
  • (Q09855) F-box/WD-repeat protein pof11 [Swiss-Prot]
  • F-box/WD repeat-containing protein pof11 OS=Schizosaccharomyces pombe GN=pof11 PE=1 SV=2 [Swiss-Prot]
  • F-BOX/WD REPEAT PROTEIN; NO APPARENT S. CEREVISIAE ORTHOLOG: Q09855;Q9P7V1; [pompepVF.fasta]
  • F-BOX/WD REPEAT PROTEIN: BAB55543;Q09855;Q9P7V1; [pompepV13]
  • F-box/WD-repeat protein pof11 [pompep4896]
  • |pof11|SPAC30.05|F-box protein [pompepnew.fasta]
  • |pof11|SPAC30.05|F-box protein|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • WD-repeat protein [Schizosaccharomyces pombe]gi|6723888|emb|CAB66464.1| SPAC30.05 [Schizosaccharomyces pombe]gi|19862893|sp|Q09855|POFB_SCHPO F-box/WD-repeat protein pof11gi|11346448|pir||T50211 WD-repeat protein [imported] - fission yeast (Schizosacc [nrdb_11152004_Chlamydomonas]
  • |pof11|SPAC30.05, mug156|F-box protein Pof11|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC29E6.01 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • F-box/WD repeat protein pof11 [nr-271106-contam.fasta]
  • F-box protein Pof11 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC30.05 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • F-box/WD repeat-containing protein pof11 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pof11 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 506 amino acids

    Gene Ontology:
    Cellular Component: ubiquitin ligase complex [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: protein ubiquitination [ISSLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    protein binding, bridging [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQDDNGKNV VSKVSDLTSC SDFSTSSPVP CLNPLSHENN RIDLIRDLLA SLSKEGVVAV  60
   61 YNHVRSLLFT DFTEVFPEEV SLRVFSYLDQ LDLCKCKLMS KRWKRLLEDP GIWKALYMQK 120
  121 GWFVNENVLN EFEAWRRTHK FPQPRFENFL KQQNIIGPYG TMFLPQQFIF DSNGRPLLNW 180
  181 SYLYKEHAHL DSNWRHGRFL VSTFNNPSIR FPADQDFRAT LDSVYCVQYD DEIMVSGSKD 240
  241 RTVSVWDVNS RFILYKLYGH SGSVLCLDFC RRRNLLVSGS SDSTIIIWDW QNRRPLKVYF 300
  301 GHTDNVLGVV VSENYIISSS RDHTARVWRL DATSPAEACM HVLRGHLASV NSVQYSSKTG 360
  361 LIVTASSDRT LRTWDITTGH CIRIIHAHQR GIACAQYNGK FIVSGSSDLT IRIFEASSGK 420
  421 LLRMLQGHED LIRTVRFNDE KIVSGGYDGT VRIWNFNTGE QHCVLHNSRN SRVFGLQFDH 480
  481 RRIIACTHSS EILVWNFDDG LDCTFF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..506] PSI-BLAST 62.0 F-box/WD-repeat protein 1 (beta-TRCP1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  7.6976390971701 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  7.38724968585043 bayes_pls_golite062009
  • dynactin binding
    		•  7.11157019623125 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  6.41826641115519 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  5.36089569430187 bayes_pls_golite062009
  • myosin heavy chain kinase activity
    		•  4.33124151198369 bayes_pls_golite062009
  • GTPase activity
    		•  4.02994814377904 bayes_pls_golite062009
  • actin binding
    		•  3.86142918698875 bayes_pls_golite062009
  • myosin II binding
    		•  3.56132510021228 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.1056443224755 bayes_pls_golite062009
  • tubulin binding
    		•  2.76945430061825 bayes_pls_golite062009
  • microtubule binding
    		•  2.72684103222924 bayes_pls_golite062009
  • dynein binding
    		•  2.54821997913979 bayes_pls_golite062009
  • peroxisome targeting sequence binding
    		•  2.43196533618619 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • ligase activity
    		•  2.30636108809275 bayes_pls_golite062009
  • protein binding
    		•  2.26925404328312 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  2.10926890165617 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.10348788067437 bayes_pls_golite062009
  • actin filament binding
    		•  2.0735069176589 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.00420268007946 bayes_pls_golite062009
  • DNA binding
    		•  1.53482914288832 bayes_pls_golite062009
  • platelet-activating factor acetyltransferase activity
    		•  1.36229564654648 bayes_pls_golite062009
  • peroxisome matrix targeting signal-2 binding
    		•  1.26984584070766 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • receptor activity
    		•  1.12819778129653 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  1.01166033978052 bayes_pls_golite062009
  • myosin binding
    		•  0.989691178611801 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • signal transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • protein transporter activity
    		•  0.964340340346761 bayes_pls_golite062009
  • type 1 angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
  • angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
  • transcription factor activity
    		•  0.897833210520351 bayes_pls_golite062009
  • kinase activity
    		•  0.807669232329985 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.805273887494167 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.734793983890004 bayes_pls_golite062009
  • transcription activator activity
    		•  0.724420384084538 bayes_pls_golite062009
  • dynein intermediate chain binding
    		•  0.707581908546932 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.634547834947756 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.624053529462119 bayes_pls_golite062009
  • protein kinase activity
    		•  0.544118712921054 bayes_pls_golite062009
  • transcription factor binding
    		•  0.469377587704245 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.446034974847705 bayes_pls_golite062009
  • insulin receptor binding
    		•  0.43316396073854 bayes_pls_golite062009
  • snoRNA binding
    		•  0.347797037104681 bayes_pls_golite062009
    		• 0.309947462700731 bayes_pls_golite062009
  • structural molecule activity
    		•  0.254012051644049 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.245000508226811 bayes_pls_golite062009
  • hydrolase activity
    		•  0.181211933860468 bayes_pls_golite062009
  • histone binding
    		•  0.166694897714113 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.161639372576406 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.118975415284669 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.0803897416817422 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.0676565515282608 bayes_pls_golite062009
  • receptor binding
    		•  0.0390635451962911 bayes_pls_golite062009
  • kinase binding
    		•  0.0366162235750993 bayes_pls_golite062009
  • protein kinase binding
    		•  0.00858004043229577 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle