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View Structure Prediction Details

Protein: pof11
Organism: Schizosaccharomyces pombe
Length: 506 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pof11.

Description E-value Query
Range		 Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
 501.0 [0..3] [505..1171]
gi|75701503, gi|... - gi|75907778|ref|YP_322074.1| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...
 480.0 [0..3] [505..1085]
gi|35214926, gi|... - gi|37523920|ref|NP_927297.1| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi|35214...
 479.0 [0..3] [505..564]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
 478.0 [0..3] [505..947]
gi|148658115, gi... - gi|148658115|ref|YP_001278320.1| NB-ARC domain-containing protein [Roseiflexus sp. RS-1], gi|1485702...
 467.0 [0..3] [505..778]
gi|116200089, gi... - gi|88179479|gb|EAQ86947.1| hypothetical protein CHGG_08200 [Chaetomium globosum CBS 148.51], gi|1162...
 463.0 [0..3] [505..952]

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Predicted Domain #1
Region A:
Residues: [1-506] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQDDNGKNV VSKVSDLTSC SDFSTSSPVP CLNPLSHENN RIDLIRDLLA SLSKEGVVAV  60
   61 YNHVRSLLFT DFTEVFPEEV SLRVFSYLDQ LDLCKCKLMS KRWKRLLEDP GIWKALYMQK 120
  121 GWFVNENVLN EFEAWRRTHK FPQPRFENFL KQQNIIGPYG TMFLPQQFIF DSNGRPLLNW 180
  181 SYLYKEHAHL DSNWRHGRFL VSTFNNPSIR FPADQDFRAT LDSVYCVQYD DEIMVSGSKD 240
  241 RTVSVWDVNS RFILYKLYGH SGSVLCLDFC RRRNLLVSGS SDSTIIIWDW QNRRPLKVYF 300
  301 GHTDNVLGVV VSENYIISSS RDHTARVWRL DATSPAEACM HVLRGHLASV NSVQYSSKTG 360
  361 LIVTASSDRT LRTWDITTGH CIRIIHAHQR GIACAQYNGK FIVSGSSDLT IRIFEASSGK 420
  421 LLRMLQGHED LIRTVRFNDE KIVSGGYDGT VRIWNFNTGE QHCVLHNSRN SRVFGLQFDH 480
  481 RRIIACTHSS EILVWNFDDG LDCTFF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.0
Match: 1p22A
Description: F-box/WD-repeat protein 1 (beta-TRCP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 7.6976390971701 bayes_pls_golite062009
small conjugating protein ligase activity 7.38724968585043 bayes_pls_golite062009
dynactin binding 7.11157019623125 bayes_pls_golite062009
acid-amino acid ligase activity 6.41826641115519 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.36089569430187 bayes_pls_golite062009
myosin heavy chain kinase activity 4.33124151198369 bayes_pls_golite062009
GTPase activity 4.02994814377904 bayes_pls_golite062009
actin binding 3.86142918698875 bayes_pls_golite062009
myosin II binding 3.56132510021228 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
peroxisome targeting sequence binding 2.43196533618619 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
ligase activity 2.30636108809275 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
G-protein-coupled receptor binding 2.10926890165617 bayes_pls_golite062009
transcription regulator activity 2.10348788067437 bayes_pls_golite062009
actin filament binding 2.0735069176589 bayes_pls_golite062009
nucleic acid binding 2.00420268007946 bayes_pls_golite062009
DNA binding 1.53482914288832 bayes_pls_golite062009
platelet-activating factor acetyltransferase activity 1.36229564654648 bayes_pls_golite062009
peroxisome matrix targeting signal-2 binding 1.26984584070766 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
receptor activity 1.12819778129653 bayes_pls_golite062009
microtubule plus-end binding 1.01166033978052 bayes_pls_golite062009
myosin binding 0.989691178611801 bayes_pls_golite062009
molecular transducer activity 0.974380908248463 bayes_pls_golite062009
signal transducer activity 0.974380908248463 bayes_pls_golite062009
protein transporter activity 0.964340340346761 bayes_pls_golite062009
type 1 angiotensin receptor binding 0.920323565472959 bayes_pls_golite062009
angiotensin receptor binding 0.920323565472959 bayes_pls_golite062009
transcription factor activity 0.897833210520351 bayes_pls_golite062009
kinase activity 0.807669232329985 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.805273887494167 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
transcription activator activity 0.724420384084538 bayes_pls_golite062009
dynein intermediate chain binding 0.707581908546932 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.634547834947756 bayes_pls_golite062009
transcription repressor activity 0.624053529462119 bayes_pls_golite062009
protein kinase activity 0.544118712921054 bayes_pls_golite062009
transcription factor binding 0.469377587704245 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.446034974847705 bayes_pls_golite062009
insulin receptor binding 0.43316396073854 bayes_pls_golite062009
snoRNA binding 0.347797037104681 bayes_pls_golite062009
0.309947462700731 bayes_pls_golite062009
structural molecule activity 0.254012051644049 bayes_pls_golite062009
transcription cofactor activity 0.245000508226811 bayes_pls_golite062009
hydrolase activity 0.181211933860468 bayes_pls_golite062009
histone binding 0.166694897714113 bayes_pls_golite062009
enzyme regulator activity 0.161639372576406 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
protein serine/threonine kinase activity 0.0803897416817422 bayes_pls_golite062009
transcription corepressor activity 0.0676565515282608 bayes_pls_golite062009
receptor binding 0.0390635451962911 bayes_pls_golite062009
kinase binding 0.0366162235750993 bayes_pls_golite062009
protein kinase binding 0.00858004043229577 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009
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