Protein Overview: csn4

General Information:
Name(s) found:	csn4 / SPAC22A12.03c [Sanger Pombe]
Description(s) found: Found 18 descriptions. SHOW ALL	COP9/signalosome complex subunit Csn4 [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	377 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytosol [IDA] signalosome [NAS]
Biological Process:	regulation of proteasomal ubiquitin-dependent protein catabolic process [NAS] cell cycle [RCA] cullin deneddylation [NAS]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEVVHYFLE GNMPVAQFRE ALALHYTNEK ELFEQAKRCL NICCGSNNFA KRNDVLFSLL  60
   61 DVAVSISSLE LRKELISELY VPVQSLEEAP SEYLVSCCLQ LATIYEAEQN FELLCSSLEA 120
  121 VEKHGHFEND LEQLLLLRIR LGDAYLKLGK AEKAILTVRT SIPLAFKVSN DQLLMELQLC 180
  181 NARALDETGQ FLEAAKCYYR VLQYKVPGNE LIYRENLCSV AQCLLLAIPS PIVLQFLQEI 240
  241 SLQPSVREIP FYSLVEKYLK RKFIGKEDGA FLLPFLLPHQ VIHMNRLIED GRHFLETNIL 300
  301 FLSEFFEVSS TSILAKHFKL SEEQVDTVVA DMVIQERLNA SIDQCEGYIT FLPEYGKANN 360
  361 LPNYVNKIAT VLQHYGS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..284]	FFAS03	1.33	Vesicular transport protein sec17
2	View Details	[285..377]	PSI-BLAST	15.69897	Solution structure of the PCI domain

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
binding	2.64850159998065	bayes_pls_golite062009
small conjugating protein ligase activity	1.60682647486188	bayes_pls_golite062009
transcription regulator activity	1.57767877959184	bayes_pls_golite062009
protein binding	1.51322932625387	bayes_pls_golite062009
ubiquitin-protein ligase activity	1.48377790267007	bayes_pls_golite062009
nucleic acid binding	1.38123254005315	bayes_pls_golite062009
DNA binding	1.32823848889363	bayes_pls_golite062009
acid-amino acid ligase activity	0.944333231961432	bayes_pls_golite062009
transcription factor activity	0.679223944174373	bayes_pls_golite062009
hydrolase activity	0.63851966218836	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.563836491184155	bayes_pls_golite062009
transcription factor binding	0.202402797164729	bayes_pls_golite062009
transferase activity	0.157308242400253	bayes_pls_golite062009

2

Term	Confidence	Notes
transcription regulator activity	4.76121492612224	bayes_pls_golite062009
DNA binding	4.45042383195146	bayes_pls_golite062009
nucleic acid binding	4.3254009446371	bayes_pls_golite062009
transcription factor activity	3.7855017556511	bayes_pls_golite062009
binding	3.52874320222492	bayes_pls_golite062009
sequence-specific DNA binding	2.23304004014963	bayes_pls_golite062009
transcription activator activity	2.05043065144612	bayes_pls_golite062009
transcription repressor activity	1.93737634607471	bayes_pls_golite062009
small conjugating protein ligase activity	1.27763700765562	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.23862224095769	bayes_pls_golite062009
ubiquitin-protein ligase activity	1.12147035668008	bayes_pls_golite062009
acid-amino acid ligase activity	0.754042916649094	bayes_pls_golite062009
protein binding	0.753698599635855	bayes_pls_golite062009
transcription factor binding	0.612315945412079	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.486434906547244	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.249771970501337	bayes_pls_golite062009
hydrolase activity	0.140191206949582	bayes_pls_golite062009
transferase activity	0.064832527337659	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.93

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle