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Protein Overview: aralar1-PD, aral...

General Information:
Name(s) found: aralar1-PD / FBpp0085057 [FlyBase]
aralar1-PA / FBpp0085056 [FlyBase]
Description(s) found:
Found 34 descriptions.
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  • The gene aralar1 is referred to in FlyBase by the symbol Dmel\aralar1 (CG2139, FBgn0028646). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26271361..26281589. It has the cytological map location 99F4-99F5. Based on sequence similarity, it is predicted to have molecular function</span>: calcium ion binding; transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial transport. 11 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • The gene aralar1 is referred to in FlyBase by the symbol Dmel\aralar1 (CG2139, FBgn0028646). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26271361..26281589. It has the cytological map location 99F4-99F5. Based on sequence similarity, it is predicted to have molecular function</span>: calcium ion binding; transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial transport. 11 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 682 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLTKSLPNS PSLLKRAGTE KLREVFLKYA SIQKNGEHYM TSEDFVRKFL GLFSESAFND  60
   61 ESVRLLANIA DTSKDGLISF SEFQAFEGLL CTPDALYRTA FQLFDRKGNG TVSYADFADV 120
  121 VQKTELHSKI PFSLDGPFIK RYFGDKKQRL INYAEFTQLL HDFHEEHAME AFRSKDPAGT 180
  181 GFISPLDFQD IIVNVKRHLL TPGVRDNLVS VTEGHKVSFP YFIAFTSLLN NMELIKQVYL 240
  241 HATEGSRTDM ITKDQILLAA QTMSQITPLE IDILFHLAGA VHQAGRIDYS DLSNIAPEHY 300
  301 TKHMTHRLAE IKAVESPADR SAFIQVLESS YRFTLGSFAG AVGATVVYPI DLVKTRMQNQ 360
  361 RAGSYIGEVA YRNSWDCFKK VVRHEGFMGL YRGLLPQLMG VAPEKAIKLT VNDLVRDKLT 420
  421 DKKGNIPTWA EVLAGGCAGA SQVVFTNPLE IVKIRLQVAG EIASGSKIRA WSVVRELGLF 480
  481 GLYKGARACL LRDVPFSAIY FPTYAHTKAM MADKDGYNHP LTLLAAGAIA GVPAASLVTP 540
  541 ADVIKTRLQV VARSGQTTYT GVWDATKKIM AEEGPRAFWK GTAARVFRSS PQFGVTLVTY 600
  601 ELLQRLFYVD FGGTQPKGSE AHKITTPLEQ AAASVTTENV DHIGGYRAAV PLLAGVESKF 660
  661 GLYLPRFGRG VTAASPSTAT GS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..178] PSI-BLAST 41.69897 Structure of calmodulin bound to a calcineurin peptide: a new way of making an old binding mode
    2 View Details [179..316] FFAS03 1.18 Apoptosis-linked protein alg-2
    3 View Details [317..682] PSI-BLAST 79.09691 structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • calcium ion binding
    		•  3.3502343978768 bayes_pls_golite062009
  • binding
    		•  2.62940555587192 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.62465453278501 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.58331384033974 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.56450760908401 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.46558208549358 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.39219065596758 bayes_pls_golite062009
  • structural molecule activity
    		•  1.98487959981447 bayes_pls_golite062009
  • potassium channel activity
    		•  1.89216151100151 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  1.80063823023387 bayes_pls_golite062009
  • motor activity
    		•  1.68044193245645 bayes_pls_golite062009
  • cation channel activity
    		•  1.4950665324992 bayes_pls_golite062009
  • actin binding
    		•  1.42596573582079 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.39455566984566 bayes_pls_golite062009
  • signal transducer activity
    		•  1.39455566984566 bayes_pls_golite062009
  • structural constituent of muscle
    		•  1.38543362753268 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.24632772915948 bayes_pls_golite062009
  • transporter activity
    		•  1.18173318787461 bayes_pls_golite062009
  • protein binding
    		•  1.09433047543741 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  1.06257290148275 bayes_pls_golite062009
  • channel activity
    		•  1.06257290148275 bayes_pls_golite062009
  • ion channel activity
    		•  1.04002358216664 bayes_pls_golite062009
  • ion binding
    		•  1.03987367434642 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  1.03912277255945 bayes_pls_golite062009
  • metal ion binding
    		•  1.02345340724535 bayes_pls_golite062009
  • cation binding
    		•  1.02345340724535 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.978447945241838 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.967232199555998 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.903772926548548 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.896570410571443 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.890153400390069 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.889351626579486 bayes_pls_golite062009
  • gated channel activity
    		•  0.857277240351281 bayes_pls_golite062009
  • DNA binding
    		•  0.846946233549871 bayes_pls_golite062009
  • tubulin binding
    		•  0.812194607648073 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  0.718077220370247 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.713088884599039 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  0.633699364706973 bayes_pls_golite062009
  • microtubule binding
    		•  0.459835151828266 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.255162242356474 bayes_pls_golite062009
  • protein complex binding
    		•  0.229066577003238 bayes_pls_golite062009
    		• 0.184502455796377 bayes_pls_golite062009
  • myosin binding
    		•  0.180486266101886 bayes_pls_golite062009
  • channel regulator activity
    		•  0.165732133218208 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0313595597352014 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.014511553141427 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.011612192141763 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.63

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle