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Protein Overview: FBpp0307575, cdm-PA

General Information:
Name(s) found: FBpp0307575 [FlyBase]
cdm-PA / FBpp0083039 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=3R:complement(14005639..14005723,14005788..14006347,14006407..14006544,14006605..14006802,14006869..14007468,14007574..14008255,14008318..14008814,14008913..14009068); ID=FBpp0307575; name=cdm-PB; parent=FBgn0261532,FBtr0336472; dbxref=REFSEQ:NP_001262696,GB_protein:AGB96076,FlyBase:FBpp0307575,FlyBase_Annotation_IDs:CG7212-PB; MD5=d693d8f17b81a54c28bd9eb8e6ff7029; length=971; release=r5.56; species=Dmel; [FlyBase]
  • The gene cadmus is referred to in FlyBase by the symbol Dmel\cdm (CG7212, FBgn0261532). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:14005435..14009201. It has the cytological map location 90F5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding; protein transporter activity. There is experimental evidence that it is involved in the biological process</span>: regulation of synaptic transmission; phototaxis; nerve-nerve synaptic transmission. 18 alleles are reported. The phenotypes of these alleles are annotated with: abdominal lateral transverse muscle 3; abdominal lateral transverse muscle 1; abdominal lateral transverse muscle 4; larval neuromuscular junction; somatic muscle; postsynaptic membrane; abdominal dorsal transverse muscle 1; abdominal lateral transverse muscle 2. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 971 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nerve-nerve synaptic transmission [IMP]
    phototaxis [IMP]
    regulation of synaptic transmission [IMP]
    intracellular protein transport [IEA]
    Molecular Function: protein transporter activity [IEA]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPIDIARLE EAVVSFYRSN SQNQAITHEW LTDAEASPQA WQFSWQLMQL GKSQEVQFFG  60
   61 AITLHSKLMK HWHEVPPENR EELKQKILES IVRFAGGPKI VLNRLCISLG AYIVHMLGEW 120
  121 PGAIEEVINT FQNQRMPNVS ADVQLWIMLE VLTAIPEEAQ VIHTSVKRVV LRAEIAKRVQ 180
  181 LVIHTVERYL KLQMNRVWDA EAYSNMNRAV KCVGTWIKNI GYTIEGCVTI TAVLLEVVHK 240
  241 CYWPCIHAGD GCMTADENEL AESCLKTMVN IIIQPDCHNY PKTAFVLIKM FLDSLSEITK 300
  301 TEWKRENDNE DIIVHIYMLF VSSVERHSTL LLSGITSADP ELSILVHRIV QEILHCTDKP 360
  361 GIYPVEESCS TMALAFWYML QDEVFAMSND EQKHKCWEYI KPLYAHLTRI LVRKSEQPDE 420
  421 KSLAKWSSDD LECFRCYRQD ISDTFMYCYD VLNDYILEIL AAMLDEAIAD LQRHPTHWTK 480
  481 LEACIYSFQS VAEHFGGEEK RQIPRLMRVL AEIPYEKLNV KLLGTALETM GSYCNWLMEN 540
  541 PAYIPPAINL LVRGLNSSMS AQATLGLKEL CRDCQLQLKP YADPLLNACH ASLNTGRMKN 600
  601 SDSVRLMFSI GKLMSLLRPE EIPKYLDIIV SPCFEELQAI CQADSKTPAA RIRTIFRLNM 660
  661 ISTLFSSLNT DVDEQATDQP IVQPVLLVMQ RTMPIFKRIA EMWVEEIDVL EAACSAMKHA 720
  721 ITNLRSSFQP MLQDLCLFIV ASFQTRCCAP TLEISKTAIV MFFKDEGCKP LMQQLLREFI 780
  781 QHSFKLFEST PEQNFSNISD TMETFFGCLT QIIKKIPQVL EDKTLAYDRL VFYAQRGMTL 840
  841 PESGAIRNSI QFLTHFVMQS RNHAHVTEVV LATGEQTLYT AMMCVGYLTP RSQVDKFADI 900
  901 LLAMNRKYAA EMAVWMKSLM STPNFPTQLI TDADKTRYTA LIIKEKVNKR LLQQHLSEMA 960
  961 MKTRGLTEKF Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..971] PSI-BLAST 86.69897 Karyopherin beta2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  3.37337719451433 bayes_pls_golite062009
  • binding
    		•  3.0667965351474 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.74745843355294 bayes_pls_golite062009
  • RNA binding
    		•  2.62683106046883 bayes_pls_golite062009
  • transporter activity
    		•  1.96378463119414 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  1.91487015967262 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.90912542848632 bayes_pls_golite062009
  • DNA binding
    		•  1.77040152722002 bayes_pls_golite062009
  • protein binding
    		•  1.73688475473996 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.65364344577652 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  1.4515576307774 bayes_pls_golite062009
  • transcription factor activity
    		•  1.27944481949335 bayes_pls_golite062009
  • mRNA binding
    		•  1.24616647164637 bayes_pls_golite062009
  • RNA cap binding
    		•  0.85485270555676 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.722899877678394 bayes_pls_golite062009
  • signal sequence binding
    		•  0.57106697498903 bayes_pls_golite062009
  • nuclear export signal receptor activity
    		•  0.501965300276747 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.439826552150332 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.100181463251306 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0797305392056347 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0635404099346928 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0548082069333885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.052195223119721 bayes_pls_golite062009
  • transcription factor binding
    		•  0.00210118982863072 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle